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CGRRF1 protein (human) - STRING interaction network
"CGRRF1" - Cell growth regulator with RING finger domain protein 1 in Homo sapiens
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
CGRRF1Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines; Ring finger proteins (332 aa)    
Predicted Functional Partners:
CGREF1
Cell growth regulator with EF hand domain protein 1; Mediates cell-cell adhesion in a calcium-dependent manner (By similarity). Able to inhibit growth in several cell lines; EF-hand domain containing (318 aa)
           
  0.931
RNF170
E3 ubiquitin-protein ligase RNF170; E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells; Ring finger proteins (258 aa)
     
   
  0.725
RNFT1
E3 ubiquitin-protein ligase RNFT1; E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome- mediated degradation. Protects cells from ER stress-induced apoptosis; Ring finger proteins (435 aa)
     
 
  0.659
RNF185
E3 ubiquitin-protein ligase RNF185; E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating ’Lys-63’-linked polyubiquitination of BNIP1. Acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis. Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway. Preferentially associates with the E2 enzymes UB [...] (192 aa)
     
   
  0.657
PLXDC2
Plexin domain-containing protein 2; May play a role in tumor angiogenesis; Belongs to the plexin family (529 aa)
           
  0.653
RNF121
Ring finger protein 121; Belongs to the RNF121 family (327 aa)
           
  0.602
RNF130
E3 ubiquitin-protein ligase RNF130; May have a role during the programmed cell death of hematopoietic cells (By similarity). Acts as an E3 ubiquitin- protein ligase; Ring finger proteins (419 aa)
     
   
  0.580
RNF180
E3 ubiquitin-protein ligase RNF180; E3 ubiquitin-protein ligase which promotes polyubiquitination and degradation by the proteasome pathway of ZIC2; Ring finger proteins (592 aa)
           
  0.576
SERAC1
Protein SERAC1; Plays an important role in the phosphatidylglycerol remodeling that is essential for both mitochondrial function and intracellular cholesterol trafficking. May catalyze the remodeling of phosphatidylglycerol and be involved in the transacylation- acylation reaction to produce phosphatidylglycerol-36-1. May be involved in bis(monoacylglycerol)phosphate biosynthetic pathway; Armadillo-like helical domain containing (654 aa)
     
   
  0.574
RNF145
Ring finger protein 145 (693 aa)
     
 
  0.573
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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