STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITIH6Inter-alpha-trypsin inhibitor heavy chain family member 6. (1313 aa)    
Predicted Functional Partners:
OR6C65
Olfactory receptor 6C65; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.667
GUCY2F
Retinal guanylyl cyclase 2; Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment (By similarity). May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (By similarity). Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
   
 
 0.546
EVX2
Even-skipped homeobox 2; Belongs to the even-skipped homeobox family.
    
   0.508
INTS6L
Integrator complex subunit 6 like.
   
  
 0.501
ZNF630
Zinc finger protein 630; May be involved in transcriptional regulation.
   
 
 0.489
AWAT1
Acyl-CoA wax alcohol acyltransferase 1; Acyltransferase that catalyzes the formation of ester bonds between fatty alcohols and fatty acyl-CoAs to form wax monoesters. Shows a strong preference for decyl alcohol (C10), with less activity towards C16 and C18 alcohols. Shows a strong preference for saturated acyl-CoAs.
   
  
 0.457
CFAP47
Cilia and flagella associated protein 47.
   
  
 0.440
SATL1
Spermidine/spermine N1-acetyl transferase like 1.
    
 
 0.439
GLT8D1
Glycosyltransferase 8 domain containing 1; Belongs to the glycosyltransferase 8 family.
      
 0.438
MTRNR2L10
Humanin-like 10; Plays a role as a neuroprotective and antiapoptotic factor. Belongs to the humanin family.
      
 0.418
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.