STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC113Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. (377 aa)    
Predicted Functional Partners:
CFAP206
Cilia- and flagella-associated protein 206; May regulate cilium motility through its role in the assembly of the axonemal radial spokes.
  
  
 0.707
LRRC23
Leucine-rich repeat-containing protein 23; Leucine rich repeat containing 23.
   
  
 0.651
DRC7
Dynein regulatory complex subunit 7; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Involved in the regulation of flagellar motility.
   
  
 0.647
CCDC153
Coiled-coil domain containing 153; Belongs to the UPF0610 family.
   
  
 0.631
KIAA1257
Uncharacterized protein KIAA1257.
   
  
 0.610
CCDC96
Coiled-coil domain containing 96.
   
 
0.602
C7orf31
Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.
   
  
 0.572
CCDC146
Coiled-coil domain containing 146.
   
  
 0.569
CFAP70
Cilia and flagella associated protein 70; Belongs to the CFAP70 family.
   
  
 0.567
CCDC81
Coiled-coil domain containing 81.
   
  
 0.556
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.