STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRSS54Serine protease 54. (395 aa)    
Predicted Functional Partners:
TEX55
Testis expressed 55.
   
  
 0.679
PRSS37
Probable inactive serine protease 37; Plays a role in male fertility (By similarity). May have a role in sperm migration or binding to zona-intact eggs (By similarity). Involved in the activation of the proacrosin/acrosin system ; Belongs to the peptidase S1 family.
   
  
 0.652
OR5C1
Olfactory receptor 5C1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.602
THEG
Testicular haploid expressed gene protein; May be involved (but not essential) in spermatogenesis.
   
  
 0.572
CT62
Cancer/testis associated 62.
      
 0.541
CPXCR1
CPX chromosome region candidate 1.
   
  
 0.531
SPATA46
Spermatogenesis-associated protein 46; Plays a role in spermiogenesis and fertilization.
   
  
 0.518
TEX37
Testis-expressed sequence 37 protein; Testis expressed 37.
   
  
 0.509
C1orf167
Uncharacterized protein C1orf167; Chromosome 1 open reading frame 167.
      
 0.479
PASD1
Circadian clock protein PASD1; Functions as a suppressor of the biological clock that drives the daily circadian rhythms of cells throughout the body. Acts as a nuclear repressor of the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock components. Inhibits circadian clock function in cancer cells, when overexpressed.
   
  
 0.464
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.