Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CRHR1 | GLCCI1 | ENSP00000381333 | ENSP00000223145 | Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...] | Glucocorticoid-induced transcript 1 protein; Glucocorticoid induced 1. | 0.522 |
| CRHR1-2 | GLCCI1 | ENSP00000488912 | ENSP00000223145 | LINC02210-CRHR1 readthrough. | Glucocorticoid-induced transcript 1 protein; Glucocorticoid induced 1. | 0.448 |
| DYNLL1 | DYRK1A | ENSP00000376297 | ENSP00000340373 | Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1; Belongs to the dynein light c [...] | Dual specificity tyrosine-phosphorylation-regulated kinase 1A; Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6 (By similarity). Exhibits a substrate preference for proline at position P+1 and arginine at position P-3. Has pro-survival function and negatively regulates the apoptotic process. Promotes cell survival upon genotoxic stress through phosphorylation of SIRT1. This in tu [...] | 0.441 |
| DYNLL1 | GLCCI1 | ENSP00000376297 | ENSP00000223145 | Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1; Belongs to the dynein light c [...] | Glucocorticoid-induced transcript 1 protein; Glucocorticoid induced 1. | 0.446 |
| DYRK1A | DYNLL1 | ENSP00000340373 | ENSP00000376297 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A; Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6 (By similarity). Exhibits a substrate preference for proline at position P+1 and arginine at position P-3. Has pro-survival function and negatively regulates the apoptotic process. Promotes cell survival upon genotoxic stress through phosphorylation of SIRT1. This in tu [...] | Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1; Belongs to the dynein light c [...] | 0.441 |
| DYRK1A | FAM53C | ENSP00000340373 | ENSP00000239906 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A; Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6 (By similarity). Exhibits a substrate preference for proline at position P+1 and arginine at position P-3. Has pro-survival function and negatively regulates the apoptotic process. Promotes cell survival upon genotoxic stress through phosphorylation of SIRT1. This in tu [...] | Protein FAM53C; Family with sequence similarity 53 member C. | 0.900 |
| DYRK1A | GLCCI1 | ENSP00000340373 | ENSP00000223145 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A; Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6 (By similarity). Exhibits a substrate preference for proline at position P+1 and arginine at position P-3. Has pro-survival function and negatively regulates the apoptotic process. Promotes cell survival upon genotoxic stress through phosphorylation of SIRT1. This in tu [...] | Glucocorticoid-induced transcript 1 protein; Glucocorticoid induced 1. | 0.772 |
| FAM53C | DYRK1A | ENSP00000239906 | ENSP00000340373 | Protein FAM53C; Family with sequence similarity 53 member C. | Dual specificity tyrosine-phosphorylation-regulated kinase 1A; Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6 (By similarity). Exhibits a substrate preference for proline at position P+1 and arginine at position P-3. Has pro-survival function and negatively regulates the apoptotic process. Promotes cell survival upon genotoxic stress through phosphorylation of SIRT1. This in tu [...] | 0.900 |
| FAM53C | GLCCI1 | ENSP00000239906 | ENSP00000223145 | Protein FAM53C; Family with sequence similarity 53 member C. | Glucocorticoid-induced transcript 1 protein; Glucocorticoid induced 1. | 0.473 |
| FBXL7 | GLCCI1 | ENSP00000423630 | ENSP00000223145 | F-box/LRR-repeat protein 7; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex. During mitosis, it mediates the ubiquitination and subsequent proteasomal degradation of AURKA, causing mitotic arrest (By similarity). It also regulates mitochondrial function by mediating the ubiquitination and proteasomal degradation of the apoptosis inhibitor BIRC5. | Glucocorticoid-induced transcript 1 protein; Glucocorticoid induced 1. | 0.451 |
| FCER2 | GLCCI1 | ENSP00000264072 | ENSP00000223145 | Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). | Glucocorticoid-induced transcript 1 protein; Glucocorticoid induced 1. | 0.539 |
| GLCCI1 | CRHR1 | ENSP00000223145 | ENSP00000381333 | Glucocorticoid-induced transcript 1 protein; Glucocorticoid induced 1. | Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...] | 0.522 |
| GLCCI1 | CRHR1-2 | ENSP00000223145 | ENSP00000488912 | Glucocorticoid-induced transcript 1 protein; Glucocorticoid induced 1. | LINC02210-CRHR1 readthrough. | 0.448 |
| GLCCI1 | DYNLL1 | ENSP00000223145 | ENSP00000376297 | Glucocorticoid-induced transcript 1 protein; Glucocorticoid induced 1. | Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1; Belongs to the dynein light c [...] | 0.446 |
| GLCCI1 | DYRK1A | ENSP00000223145 | ENSP00000340373 | Glucocorticoid-induced transcript 1 protein; Glucocorticoid induced 1. | Dual specificity tyrosine-phosphorylation-regulated kinase 1A; Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6 (By similarity). Exhibits a substrate preference for proline at position P+1 and arginine at position P-3. Has pro-survival function and negatively regulates the apoptotic process. Promotes cell survival upon genotoxic stress through phosphorylation of SIRT1. This in tu [...] | 0.772 |
| GLCCI1 | FAM53C | ENSP00000223145 | ENSP00000239906 | Glucocorticoid-induced transcript 1 protein; Glucocorticoid induced 1. | Protein FAM53C; Family with sequence similarity 53 member C. | 0.473 |
| GLCCI1 | FBXL7 | ENSP00000223145 | ENSP00000423630 | Glucocorticoid-induced transcript 1 protein; Glucocorticoid induced 1. | F-box/LRR-repeat protein 7; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex. During mitosis, it mediates the ubiquitination and subsequent proteasomal degradation of AURKA, causing mitotic arrest (By similarity). It also regulates mitochondrial function by mediating the ubiquitination and proteasomal degradation of the apoptosis inhibitor BIRC5. | 0.451 |
| GLCCI1 | FCER2 | ENSP00000223145 | ENSP00000264072 | Glucocorticoid-induced transcript 1 protein; Glucocorticoid induced 1. | Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). | 0.539 |
| GLCCI1 | ICA1 | ENSP00000223145 | ENSP00000403982 | Glucocorticoid-induced transcript 1 protein; Glucocorticoid induced 1. | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | 0.483 |
| GLCCI1 | OR6X1 | ENSP00000223145 | ENSP00000333724 | Glucocorticoid-induced transcript 1 protein; Glucocorticoid induced 1. | Olfactory receptor 6X1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.447 |
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