STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TVP23CTrans-golgi network vesicle protein 23 homolog C; Belongs to the TVP23 family. (276 aa)    
Predicted Functional Partners:
CDRT4
CMT1A duplicated region transcript 4.
 
 
  
 0.742
CDRT15
CMT1A duplicated region transcript 15.
      
 0.579
CCDC182
Coiled-coil domain containing 182.
   
  
 0.520
ULK2
Serine/threonine-protein kinase ULK2; Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and a negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK, also acts as a negative regulator of AMPK through phosphorylation of the AMPK subunits PRKAA1, PRKAB2 and PRKAG1 [...]
   
   0.495
ULK1
Serine/threonine-protein kinase ULK1; Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leadi [...]
    
   0.493
UBAP1L
Ubiquitin-associated protein 1-like; Ubiquitin associated protein 1 like.
      
 0.479
SMCO2
Single-pass membrane protein with coiled-coil domains 2.
      
 0.447
TEKT3
Tektin-3; May be a structural component of the sperm flagellum. Required for normal sperm mobility.
   
  
 0.422
PDIK1L
Serine/threonine-protein kinase PDIK1L; PDLIM1 interacting kinase 1 like.
    
   0.404
STK35
Serine/threonine kinase 35.
    
   0.404
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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