node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKFN1 | C17orf67 | ENSP00000321627 | ENSP00000380959 | Ankyrin repeat and fibronectin type III domain containing 1. | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67. | 0.561 |
ANKFN1 | SYNGR2 | ENSP00000321627 | ENSP00000467600 | Ankyrin repeat and fibronectin type III domain containing 1. | Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family. | 0.470 |
C17orf67 | ANKFN1 | ENSP00000380959 | ENSP00000321627 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67. | Ankyrin repeat and fibronectin type III domain containing 1. | 0.561 |
C17orf67 | SYNGR2 | ENSP00000380959 | ENSP00000467600 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67. | Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family. | 0.435 |
CANX | SYNGR2 | ENSP00000247461 | ENSP00000467600 | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family. | 0.642 |
CANX | TMC6 | ENSP00000247461 | ENSP00000465261 | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | Transmembrane channel-like protein 6; Probable ion channel; Belongs to the TMC family. | 0.741 |
CANX | TMC8 | ENSP00000247461 | ENSP00000325561 | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | Transmembrane channel-like protein 8; Probable ion channel; Belongs to the TMC family. | 0.730 |
SCARA3 | SYNGR2 | ENSP00000301904 | ENSP00000467600 | Scavenger receptor class A member 3; Seems to protect cells by scavenging oxidative molecules or harmful products of oxidation. | Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family. | 0.510 |
SYNGR2 | ANKFN1 | ENSP00000467600 | ENSP00000321627 | Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family. | Ankyrin repeat and fibronectin type III domain containing 1. | 0.470 |
SYNGR2 | C17orf67 | ENSP00000467600 | ENSP00000380959 | Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family. | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67. | 0.435 |
SYNGR2 | CANX | ENSP00000467600 | ENSP00000247461 | Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family. | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | 0.642 |
SYNGR2 | SCARA3 | ENSP00000467600 | ENSP00000301904 | Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family. | Scavenger receptor class A member 3; Seems to protect cells by scavenging oxidative molecules or harmful products of oxidation. | 0.510 |
SYNGR2 | SYNPR | ENSP00000467600 | ENSP00000418994 | Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family. | Synaptoporin; Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity); Belongs to the synaptophysin/synaptobrevin family. | 0.744 |
SYNGR2 | TAB1 | ENSP00000467600 | ENSP00000216160 | Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family. | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis. | 0.521 |
SYNGR2 | TK1 | ENSP00000467600 | ENSP00000468425 | Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family. | Thymidine kinase, cytosolic; Thymidine kinase 1; Belongs to the thymidine kinase family. | 0.743 |
SYNGR2 | TMC6 | ENSP00000467600 | ENSP00000465261 | Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family. | Transmembrane channel-like protein 6; Probable ion channel; Belongs to the TMC family. | 0.907 |
SYNGR2 | TMC8 | ENSP00000467600 | ENSP00000325561 | Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family. | Transmembrane channel-like protein 8; Probable ion channel; Belongs to the TMC family. | 0.926 |
SYNGR2 | TMEM235 | ENSP00000467600 | ENSP00000402790 | Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family. | Transmembrane protein 235; Belongs to the PMP-22/EMP/MP20 family. | 0.446 |
SYNPR | SYNGR2 | ENSP00000418994 | ENSP00000467600 | Synaptoporin; Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity); Belongs to the synaptophysin/synaptobrevin family. | Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family. | 0.744 |
TAB1 | SYNGR2 | ENSP00000216160 | ENSP00000467600 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis. | Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family. | 0.521 |