Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RERGLRas-related and estrogen-regulated growth inhibitor-like protein; Binds GDP/GTP and may possess intrinsic GTPase activity. (205 aa)    
Predicted Functional Partners:
MAP3K7CL
MAP3K7 C-terminal-like protein; MAP3K7 C-terminal like.
   
 
 0.526
FAM110D
Protein FAM110D; Family with sequence similarity 110 member D; Belongs to the FAM110 family.
   
  
 0.519
ANKRD61
Ankyrin repeat domain 61.
      
 0.504
FHL5
Four and a half LIM domains protein 5; May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation- independent manner.
   
 
 0.501
ARL10
ADP-ribosylation factor-like protein 10; ADP ribosylation factor like GTPase 10; Belongs to the small GTPase superfamily. Arf family.
      
 0.472
ARL9
ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9.
      
 0.462
ARL13A
ADP-ribosylation factor-like protein 13A; ADP ribosylation factor like GTPase 13A.
    
 
 0.438
QRFP
Orexigenic neuropeptide QRFP; Stimulates feeding behavior, metabolic rate and locomotor activity and increases blood pressure. May have orexigenic activity. May promote aldosterone secretion by the adrenal gland (By similarity). Belongs to the RFamide neuropeptide family.
      
 0.423
MYH11
Myosin-11; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
  
 0.417
TMEM235
Transmembrane protein 235; Belongs to the PMP-22/EMP/MP20 family.
   
  
 0.403
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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