STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UNC93AUnc-93 homolog A. (457 aa)    
Predicted Functional Partners:
MFSD9
Major facilitator superfamily domain containing 9.
   
  
 0.692
SVOPL
Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily.
      
 0.637
SVOP
Synaptic vesicle 2-related protein; SV2 related protein.
   
  
 0.620
MFSD10
Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non- steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump; Belongs to the major facilitator superfamily.
      
 0.614
BRCA1
Breast cancer type 1 susceptibility protein; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic [...]
   
 
 0.610
MFSD5
Molybdate-anion transporter; Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum; Belongs to the major facilitator superfamily.
   
  
 0.579
MFSD13A
Transmembrane protein 180; Major facilitator superfamily domain containing 13A.
      
 0.577
MFSD6
Major facilitator superfamily domain containing 6; Belongs to the major facilitator superfamily. MFSD6 family.
      
 0.560
MFSD6L
Major facilitator superfamily domain containing 6 like.
      
 0.547
MFSD14A
Hippocampus abundant transcript 1 protein; Major facilitator superfamily domain containing 14A.
      
 0.545
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.