DAZAP1 protein (human) - STRING interaction network

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Score

DAZAP1

DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis. (407 aa)

Predicted Functional Partners:

DAZAP2

0.929

MSI2

0.922

MSI1

0.920

DAZL

0.816

FOXA1

0.806

WWOX

0.802

NANS

0.792

TP53BP1

0.769

FUBP3

0.768

RBM12

0.767

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DAZAP1	DAZAP2	ENSP00000233078	ENSP00000448051	DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis.	DAZ associated protein 2.	0.929
DAZAP1	DAZL	ENSP00000233078	ENSP00000250863	DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis.	Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity); Belongs to the RRM DAZ family.	0.816
DAZAP1	FOXA1	ENSP00000233078	ENSP00000250448	DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis.	Hepatocyte nuclear factor 3-alpha; Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'- [AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). Proposed to play a role in translating the epigenetic signatures [...]	0.806
DAZAP1	FUBP3	ENSP00000233078	ENSP00000318177	DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis.	Far upstream element-binding protein 3; May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression.	0.768
DAZAP1	MSI1	ENSP00000233078	ENSP00000257552	DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis.	RNA-binding protein Musashi homolog 1; RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU- 3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity); Belongs to the Musashi family.	0.920
DAZAP1	MSI2	ENSP00000233078	ENSP00000284073	DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis.	RNA-binding protein Musashi homolog 2; RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity); Belongs to the Musashi family.	0.922
DAZAP1	NANS	ENSP00000233078	ENSP00000210444	DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis.	Sialic acid synthase; Produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy- D-glycero-D-galacto-nononic acid (KDN). Can also use N- acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.	0.792
DAZAP1	RBM12	ENSP00000233078	ENSP00000363228	DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis.	RNA binding motif protein 12.	0.767
DAZAP1	TP53BP1	ENSP00000233078	ENSP00000371475	DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis.	TP53-binding protein 1; Double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis. Plays a key role in the repair of double-strand DNA breaks (DSBs) in response to DNA damage by promoting non-homologous end joining (NHEJ)- mediated repair of DSBs and specifically counteracting the function of the homologous recombination (HR) repair protein BRCA1. In response to DSBs, phosphorylation by ATM promotes interaction with RIF1 and dissociation from NUDT16L1/TIRR, leading to recruitment to DSBs s [...]	0.769
DAZAP1	WWOX	ENSP00000233078	ENSP00000457230	DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis.	WW domain-containing oxidoreductase; Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.	0.802
DAZAP2	DAZAP1	ENSP00000448051	ENSP00000233078	DAZ associated protein 2.	DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis.	0.929
DAZAP2	DAZL	ENSP00000448051	ENSP00000250863	DAZ associated protein 2.	Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity); Belongs to the RRM DAZ family.	0.948
DAZL	DAZAP1	ENSP00000250863	ENSP00000233078	Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity); Belongs to the RRM DAZ family.	DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis.	0.816
DAZL	DAZAP2	ENSP00000250863	ENSP00000448051	Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity); Belongs to the RRM DAZ family.	DAZ associated protein 2.	0.948
FOXA1	DAZAP1	ENSP00000250448	ENSP00000233078	Hepatocyte nuclear factor 3-alpha; Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'- [AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). Proposed to play a role in translating the epigenetic signatures [...]	DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis.	0.806
FOXA1	FUBP3	ENSP00000250448	ENSP00000318177	Hepatocyte nuclear factor 3-alpha; Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'- [AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). Proposed to play a role in translating the epigenetic signatures [...]	Far upstream element-binding protein 3; May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression.	0.472
FOXA1	MSI2	ENSP00000250448	ENSP00000284073	Hepatocyte nuclear factor 3-alpha; Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'- [AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). Proposed to play a role in translating the epigenetic signatures [...]	RNA-binding protein Musashi homolog 2; RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity); Belongs to the Musashi family.	0.502
FUBP3	DAZAP1	ENSP00000318177	ENSP00000233078	Far upstream element-binding protein 3; May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression.	DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis.	0.768
FUBP3	FOXA1	ENSP00000318177	ENSP00000250448	Far upstream element-binding protein 3; May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression.	Hepatocyte nuclear factor 3-alpha; Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'- [AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). Proposed to play a role in translating the epigenetic signatures [...]	0.472
MSI1	DAZAP1	ENSP00000257552	ENSP00000233078	RNA-binding protein Musashi homolog 1; RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU- 3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity); Belongs to the Musashi family.	DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis.	0.920