C1orf21 protein (human) - STRING interaction network

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Score

C1orf21

Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21. (121 aa)

Predicted Functional Partners:

PPP2R5A

0.875

PPP2R5B

0.779

TMEM185A

0.775

PPP2R5E

0.637

DRAM1

0.571

RBBP8NL

0.418

PPP2R1B

0.408

CLIC3

0.406

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1orf21	CLIC3	ENSP00000235307	ENSP00000419378	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21.	Chloride intracellular channel protein 3; Can insert into membranes and form chloride ion channels. May participate in cellular growth control; Belongs to the chloride channel CLIC family.	0.406
C1orf21	DRAM1	ENSP00000235307	ENSP00000258534	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21.	DNA damage-regulated autophagy modulator protein 1; Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.	0.571
C1orf21	PPP2R1B	ENSP00000235307	ENSP00000311344	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21.	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.	0.408
C1orf21	PPP2R5A	ENSP00000235307	ENSP00000261461	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	0.875
C1orf21	PPP2R5B	ENSP00000235307	ENSP00000164133	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform; As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.	0.779
C1orf21	PPP2R5E	ENSP00000235307	ENSP00000337641	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment; Belongs to the phosphatase 2A regulatory subunit B56 family.	0.637
C1orf21	RBBP8NL	ENSP00000235307	ENSP00000252998	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21.	RBBP8 N-terminal-like protein; RBBP8 N-terminal like.	0.418
C1orf21	TMEM185A	ENSP00000235307	ENSP00000471932	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21.	Transmembrane protein 185A; Belongs to the TMEM185 family.	0.775
CLIC3	C1orf21	ENSP00000419378	ENSP00000235307	Chloride intracellular channel protein 3; Can insert into membranes and form chloride ion channels. May participate in cellular growth control; Belongs to the chloride channel CLIC family.	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21.	0.406
DRAM1	C1orf21	ENSP00000258534	ENSP00000235307	DNA damage-regulated autophagy modulator protein 1; Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21.	0.571
PPP2R1B	C1orf21	ENSP00000311344	ENSP00000235307	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21.	0.408
PPP2R1B	PPP2R5A	ENSP00000311344	ENSP00000261461	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	0.999
PPP2R1B	PPP2R5B	ENSP00000311344	ENSP00000164133	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform; As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.	0.993
PPP2R1B	PPP2R5E	ENSP00000311344	ENSP00000337641	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment; Belongs to the phosphatase 2A regulatory subunit B56 family.	0.999
PPP2R5A	C1orf21	ENSP00000261461	ENSP00000235307	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21.	0.875
PPP2R5A	PPP2R1B	ENSP00000261461	ENSP00000311344	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.	0.999
PPP2R5A	PPP2R5B	ENSP00000261461	ENSP00000164133	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform; As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.	0.946
PPP2R5A	PPP2R5E	ENSP00000261461	ENSP00000337641	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment; Belongs to the phosphatase 2A regulatory subunit B56 family.	0.995
PPP2R5B	C1orf21	ENSP00000164133	ENSP00000235307	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform; As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21.	0.779
PPP2R5B	PPP2R1B	ENSP00000164133	ENSP00000311344	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform; As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.	0.993