node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARL14EP | OSCP1 | ENSP00000282032 | ENSP00000349052 | ARL14 effector protein; Through its interaction with ARL14 and MYO1E, may connect MHC class II-containing cytoplasmic vesicles to the actin network and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells. | Protein OSCP1; May be involved in drug clearance in the placenta. | 0.465 |
DEFB125 | OSCP1 | ENSP00000371847 | ENSP00000349052 | Beta-defensin 125; Has antibacterial activity; Belongs to the beta-defensin family. | Protein OSCP1; May be involved in drug clearance in the placenta. | 0.420 |
GYG2 | OSCP1 | ENSP00000370555 | ENSP00000349052 | Glycogenin-2; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. | Protein OSCP1; May be involved in drug clearance in the placenta. | 0.597 |
IKZF4 | OSCP1 | ENSP00000448419 | ENSP00000349052 | Zinc finger protein Eos; DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros- binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Essential for the inhibitory function of regulatory T-cells (Treg). Mediates FOXP3- mediated gene silencing in regulatory T-cells (Treg) via recruitment of corepressor CTBP1 (By similarity). | Protein OSCP1; May be involved in drug clearance in the placenta. | 0.421 |
MORN2 | OSCP1 | ENSP00000386563 | ENSP00000349052 | MORN repeat-containing protein 2; Might have a role in spermatogenesis. | Protein OSCP1; May be involved in drug clearance in the placenta. | 0.420 |
MRPS15 | OSCP1 | ENSP00000362208 | ENSP00000349052 | Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family. | Protein OSCP1; May be involved in drug clearance in the placenta. | 0.489 |
MRPS15 | STK40 | ENSP00000362208 | ENSP00000362222 | Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family. | Serine/threonine-protein kinase 40; May be a negative regulator of NF-kappa-B and p53-mediated gene transcription. | 0.440 |
NPM2 | OSCP1 | ENSP00000381032 | ENSP00000349052 | Nucleoplasmin-2; Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization. Belongs to the nucleoplasmin family. | Protein OSCP1; May be involved in drug clearance in the placenta. | 0.454 |
OSCP1 | ARL14EP | ENSP00000349052 | ENSP00000282032 | Protein OSCP1; May be involved in drug clearance in the placenta. | ARL14 effector protein; Through its interaction with ARL14 and MYO1E, may connect MHC class II-containing cytoplasmic vesicles to the actin network and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells. | 0.465 |
OSCP1 | DEFB125 | ENSP00000349052 | ENSP00000371847 | Protein OSCP1; May be involved in drug clearance in the placenta. | Beta-defensin 125; Has antibacterial activity; Belongs to the beta-defensin family. | 0.420 |
OSCP1 | GYG2 | ENSP00000349052 | ENSP00000370555 | Protein OSCP1; May be involved in drug clearance in the placenta. | Glycogenin-2; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. | 0.597 |
OSCP1 | IKZF4 | ENSP00000349052 | ENSP00000448419 | Protein OSCP1; May be involved in drug clearance in the placenta. | Zinc finger protein Eos; DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros- binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Essential for the inhibitory function of regulatory T-cells (Treg). Mediates FOXP3- mediated gene silencing in regulatory T-cells (Treg) via recruitment of corepressor CTBP1 (By similarity). | 0.421 |
OSCP1 | MORN2 | ENSP00000349052 | ENSP00000386563 | Protein OSCP1; May be involved in drug clearance in the placenta. | MORN repeat-containing protein 2; Might have a role in spermatogenesis. | 0.420 |
OSCP1 | MRPS15 | ENSP00000349052 | ENSP00000362208 | Protein OSCP1; May be involved in drug clearance in the placenta. | Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family. | 0.489 |
OSCP1 | NPM2 | ENSP00000349052 | ENSP00000381032 | Protein OSCP1; May be involved in drug clearance in the placenta. | Nucleoplasmin-2; Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization. Belongs to the nucleoplasmin family. | 0.454 |
OSCP1 | STK40 | ENSP00000349052 | ENSP00000362222 | Protein OSCP1; May be involved in drug clearance in the placenta. | Serine/threonine-protein kinase 40; May be a negative regulator of NF-kappa-B and p53-mediated gene transcription. | 0.431 |
OSCP1 | USP16 | ENSP00000349052 | ENSP00000334808 | Protein OSCP1; May be involved in drug clearance in the placenta. | Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiqu [...] | 0.478 |
OSCP1 | WDR54 | ENSP00000349052 | ENSP00000006526 | Protein OSCP1; May be involved in drug clearance in the placenta. | WD repeat-containing protein 54; When cross-linked to form dimers and trimers, it has a regulatory effect on ERK signaling pathway activity in response to EGF stimulation. Colocalizes with the EGF receptor in WDR54-specific vesicle where it sustains the internalization and controls the degradation of the EGF receptor after EGF stimulation. | 0.784 |
STK40 | MRPS15 | ENSP00000362222 | ENSP00000362208 | Serine/threonine-protein kinase 40; May be a negative regulator of NF-kappa-B and p53-mediated gene transcription. | Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family. | 0.440 |
STK40 | OSCP1 | ENSP00000362222 | ENSP00000349052 | Serine/threonine-protein kinase 40; May be a negative regulator of NF-kappa-B and p53-mediated gene transcription. | Protein OSCP1; May be involved in drug clearance in the placenta. | 0.431 |