node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADAT1 | ADAT2 | ENSP00000310015 | ENSP00000237283 | tRNA-specific adenosine deaminase 1; Specifically deaminates adenosine-37 to inosine in tRNA-Ala. | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs. | 0.931 |
ADAT1 | ADAT3 | ENSP00000310015 | ENSP00000332448 | tRNA-specific adenosine deaminase 1; Specifically deaminates adenosine-37 to inosine in tRNA-Ala. | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily. | 0.953 |
ADAT2 | ADAT1 | ENSP00000237283 | ENSP00000310015 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs. | tRNA-specific adenosine deaminase 1; Specifically deaminates adenosine-37 to inosine in tRNA-Ala. | 0.931 |
ADAT2 | ADAT3 | ENSP00000237283 | ENSP00000332448 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs. | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily. | 0.999 |
ADAT2 | EP300 | ENSP00000237283 | ENSP00000263253 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs. | Histone acetyltransferase p300; Functions as histone acetyltransferase and regulates transcription via chromatin remodeling. Acetylates all four core histones in nucleosomes. Histone acetylation gives an epigenetic tag for transcriptional activation. Mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. Mediates acetylation of histone H3 at 'Lys-122' (H3K122ac), a modification that localizes at the surface of the histone octamer and stimulates transcription, possibly by promoting nucleosome instability. Mediates acetylation of histone H3 at 'Lys-27' (H3K [...] | 0.720 |
ADAT2 | GNRH2 | ENSP00000237283 | ENSP00000245983 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs. | GnRH-associated peptide 2; Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones; Belongs to the GnRH family. | 0.712 |
ADAT2 | GTF2H1 | ENSP00000237283 | ENSP00000265963 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs. | General transcription factor IIH subunit 1; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFII [...] | 0.771 |
ADAT2 | NT5E | ENSP00000237283 | ENSP00000257770 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs. | 5'-nucleotidase; Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities. | 0.754 |
ADAT2 | RPSA | ENSP00000237283 | ENSP00000389351 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs. | 40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. (Microbial infection) Acts as a receptor for the Dengue virus [...] | 0.779 |
ADAT2 | TK1 | ENSP00000237283 | ENSP00000468425 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs. | Thymidine kinase, cytosolic; Thymidine kinase 1; Belongs to the thymidine kinase family. | 0.754 |
ADAT2 | TYMS | ENSP00000237283 | ENSP00000315644 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs. | Thymidylate synthase; Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. | 0.823 |
ADAT2 | UPRT | ENSP00000237283 | ENSP00000362481 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs. | Uracil phosphoribosyltransferase homolog; Belongs to the UPRTase family. | 0.772 |
ADAT3 | ADAT1 | ENSP00000332448 | ENSP00000310015 | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily. | tRNA-specific adenosine deaminase 1; Specifically deaminates adenosine-37 to inosine in tRNA-Ala. | 0.953 |
ADAT3 | ADAT2 | ENSP00000332448 | ENSP00000237283 | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily. | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs. | 0.999 |
ADAT3 | NT5E | ENSP00000332448 | ENSP00000257770 | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily. | 5'-nucleotidase; Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities. | 0.752 |
ADAT3 | TK1 | ENSP00000332448 | ENSP00000468425 | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily. | Thymidine kinase, cytosolic; Thymidine kinase 1; Belongs to the thymidine kinase family. | 0.761 |
ADAT3 | TYMS | ENSP00000332448 | ENSP00000315644 | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily. | Thymidylate synthase; Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. | 0.810 |
ADAT3 | UPRT | ENSP00000332448 | ENSP00000362481 | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily. | Uracil phosphoribosyltransferase homolog; Belongs to the UPRTase family. | 0.770 |
EP300 | ADAT2 | ENSP00000263253 | ENSP00000237283 | Histone acetyltransferase p300; Functions as histone acetyltransferase and regulates transcription via chromatin remodeling. Acetylates all four core histones in nucleosomes. Histone acetylation gives an epigenetic tag for transcriptional activation. Mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. Mediates acetylation of histone H3 at 'Lys-122' (H3K122ac), a modification that localizes at the surface of the histone octamer and stimulates transcription, possibly by promoting nucleosome instability. Mediates acetylation of histone H3 at 'Lys-27' (H3K [...] | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs. | 0.720 |
GNRH2 | ADAT2 | ENSP00000245983 | ENSP00000237283 | GnRH-associated peptide 2; Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones; Belongs to the GnRH family. | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs. | 0.712 |