Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
YIPF4Protein YIPF4; Involved in the maintenance of the Golgi structure. Belongs to the YIP1 family. (244 aa)    
Predicted Functional Partners:
YIPF3
Protein YIPF3, 36 kDa form III; Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
   
 
 0.994
YIF1A
Protein YIF1A; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the YIF1 family.
   
 
 0.825
YIPF2
Protein YIPF2; Yip1 domain family member 2.
   
 
 0.751
YIPF1
Protein YIPF1; Yip1 domain family member 1; Belongs to the YIP1 family.
   
 
 0.697
YIF1B
Protein YIF1B; Yip1 interacting factor homolog B, membrane trafficking protein.
   
 
 0.668
TVP23B
Trans-golgi network vesicle protein 23 homolog B; Belongs to the TVP23 family.
   
 
 0.637
NKAP
NF-kappa-B-activating protein; Acts as a transcriptional repressor. Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development. Also involved in the TNF and IL-1 induced NF- kappa-B activation. Associates with chromatin at the Notch-regulated SKP2 promoter; Belongs to the NKAP family.
   
   0.551
ZNF324B
Zinc finger protein 324B; May be involved in transcriptional regulation.
      
 0.548
IER3IP1
Immediate early response 3-interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus (By similarity); Belongs to the YOS1 family.
   
 
 0.534
RABAC1
Prenylated Rab acceptor protein 1; General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI. Belongs to the PRA1 family.
   
 
 0.506
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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