Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
MFSD13ATransmembrane protein 180; Major facilitator superfamily domain containing 13A. (517 aa)    
Predicted Functional Partners:
MFSD9
Major facilitator superfamily domain containing 9.
   
  
 0.635
MFSD11
UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family.
   
  
 0.607
MFSD6L
Major facilitator superfamily domain containing 6 like.
      
 0.595
MFSD5
Molybdate-anion transporter; Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum; Belongs to the major facilitator superfamily.
   
  
 0.578
BORCS7
BLOC-1-related complex subunit 7; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Belongs to the BORCS7 family.
      
 0.571
MFSD12
Major facilitator superfamily domain containing 12.
   
  
 0.565
AS3MT
Arsenite methyltransferase; Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH.
      
 0.562
MFSD6
Major facilitator superfamily domain containing 6; Belongs to the major facilitator superfamily. MFSD6 family.
      
 0.550
UNC93A
Unc-93 homolog A.
      
 0.544
FBXL15
F-box/LRR-repeat protein 15; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.
   
  
 0.538
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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