STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC77Coiled-coil domain containing 77. (488 aa)    
Predicted Functional Partners:
CCDC14
Coiled-coil domain-containing protein 14; Negatively regulates centriole duplication. Negatively regulates CEP63 and CDK2 centrosomal localization.
   
 
 0.699
C18orf54
Chromosome 18 open reading frame 54.
   
  
 0.645
NEMP1
Nuclear envelope integral membrane protein 1.
   
  
 0.618
CCDC150
Coiled-coil domain containing 150.
   
  
 0.616
CEP85
Centrosomal protein of 85 kDa; Acts as a negative regulator of NEK2 to maintain the centrosome integrity in interphase. Suppresses centrosome disjunction by inhibiting NEK2 kinase activity. Belongs to the CEP85 family.
   
  
 0.575
C3orf14
Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14.
   
  
 0.560
DEPDC1B
DEP domain containing 1B.
   
  
 0.546
CCDC34
Coiled-coil domain containing 34.
   
  
 0.545
GSTCD
Glutathione S-transferase C-terminal domain containing; Belongs to the GSTCD family.
   
  
 0.545
TEX52
Testis-expressed protein 52; Testis expressed 52.
      
 0.542
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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