node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD13D | ENKD1 | ENSP00000427130 | ENSP00000243878 | Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. | Enkurin domain containing 1. | 0.454 |
C1orf35 | ENKD1 | ENSP00000272139 | ENSP00000243878 | Multiple myeloma tumor-associated protein 2; Chromosome 1 open reading frame 35. | Enkurin domain containing 1. | 0.439 |
CALY | CLHC1 | ENSP00000252939 | ENSP00000384869 | Neuron-specific vesicular protein calcyon; Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis. | Clathrin heavy chain linker domain containing 1. | 0.409 |
CALY | ENKD1 | ENSP00000252939 | ENSP00000243878 | Neuron-specific vesicular protein calcyon; Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis. | Enkurin domain containing 1. | 0.474 |
CLHC1 | CALY | ENSP00000384869 | ENSP00000252939 | Clathrin heavy chain linker domain containing 1. | Neuron-specific vesicular protein calcyon; Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis. | 0.409 |
CLHC1 | ENKD1 | ENSP00000384869 | ENSP00000243878 | Clathrin heavy chain linker domain containing 1. | Enkurin domain containing 1. | 0.561 |
CLHC1 | SCRN1 | ENSP00000384869 | ENSP00000388942 | Clathrin heavy chain linker domain containing 1. | Secernin-1; Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity). | 0.520 |
ENKD1 | ANKRD13D | ENSP00000243878 | ENSP00000427130 | Enkurin domain containing 1. | Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. | 0.454 |
ENKD1 | C1orf35 | ENSP00000243878 | ENSP00000272139 | Enkurin domain containing 1. | Multiple myeloma tumor-associated protein 2; Chromosome 1 open reading frame 35. | 0.439 |
ENKD1 | CALY | ENSP00000243878 | ENSP00000252939 | Enkurin domain containing 1. | Neuron-specific vesicular protein calcyon; Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis. | 0.474 |
ENKD1 | CLHC1 | ENSP00000243878 | ENSP00000384869 | Enkurin domain containing 1. | Clathrin heavy chain linker domain containing 1. | 0.561 |
ENKD1 | GFOD2 | ENSP00000243878 | ENSP00000268797 | Enkurin domain containing 1. | Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly. | 0.760 |
ENKD1 | PNMA1 | ENSP00000243878 | ENSP00000318914 | Enkurin domain containing 1. | Paraneoplastic antigen Ma1; PNMA family member 1; Belongs to the PNMA family. | 0.430 |
ENKD1 | SCRN1 | ENSP00000243878 | ENSP00000388942 | Enkurin domain containing 1. | Secernin-1; Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity). | 0.416 |
ENKD1 | SLC49A3 | ENSP00000243878 | ENSP00000384616 | Enkurin domain containing 1. | Solute carrier family 49 member 3; Belongs to the major facilitator superfamily. | 0.427 |
ENKD1 | STAC3 | ENSP00000243878 | ENSP00000329200 | Enkurin domain containing 1. | SH3 and cysteine-rich domain-containing protein 3; Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction. Probably functions via its effects on muscle calcium channels. Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane. Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membran [...] | 0.420 |
ENKD1 | TMEM129 | ENSP00000243878 | ENSP00000372394 | Enkurin domain containing 1. | E3 ubiquitin-protein ligase TM129; E3 ubiquitin-protein ligase involved in ER-associated protein degradation, preferentially associates with the E2 enzyme UBE2J2. Exploited by viral US11 proteins to mediate HLA class I proteins degradation. | 0.560 |
GFOD2 | ENKD1 | ENSP00000268797 | ENSP00000243878 | Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly. | Enkurin domain containing 1. | 0.760 |
PNMA1 | ENKD1 | ENSP00000318914 | ENSP00000243878 | Paraneoplastic antigen Ma1; PNMA family member 1; Belongs to the PNMA family. | Enkurin domain containing 1. | 0.430 |
SCRN1 | CLHC1 | ENSP00000388942 | ENSP00000384869 | Secernin-1; Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity). | Clathrin heavy chain linker domain containing 1. | 0.520 |