STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF391Zinc finger protein 391; May be involved in transcriptional regulation; Zinc fingers C2H2-type (358 aa)    
Predicted Functional Partners:
SAPCD1
Suppressor APC domain containing 1
      
 0.631
OR2H1
Olfactory receptor 2H1; Odorant receptor; Olfactory receptors, family 2
      
 0.626
C5orf34
Uncharacterized protein C5orf34; Chromosome 5 open reading frame 34
      
 0.615
LRRC36
Leucine-rich repeat-containing protein 36; Leucine rich repeat containing 36
      
 0.559
TMEM178A
Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1; Belongs to the TMEM178 family
      
 0.557
MRPL42
Mitochondrial ribosomal protein L42; Belongs to the mitochondrion-specific ribosomal protein mL42 family
      
 0.491
ZDHHC15
Palmitoyltransferase ZDHHC15; Palmitoyltransferase specific for GAP43 and DLG4/PSD95; Belongs to the DHHC palmitoyltransferase family
   
 
 0.489
CYTH4
Cytohesin-4; Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP; Pleckstrin homology domain containing
      
 0.474
PGM5
Phosphoglucomutase-like protein 5; Component of adherens-type cell-cell and cell-matrix junctions. Lacks phosphoglucomutase activity
   
  
 0.451
CYP4Z1
Cytochrome P450 family 4 subfamily Z member 1
    
 
 0.427
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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