STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CFAP61Cilia- and flagella-associated protein 61; May regulate cilium motility through its role in the assembly of the axonemal radial spokes. (1237 aa)    
Predicted Functional Partners:
MAATS1
Cilia- and flagella-associated protein 91; May play a role in spermatogenesis. May regulate cilium motility through its role in the assembly of the axonemal radial spokes (By similarity).
   
 
 0.805
WDR66
Cilia- and flagella-associated protein 251; Involved in spermatozoa motility. May also regulate cilium motility through its role in the assembly of the axonemal radial spokes (By similarity).
   
 
 0.795
CFAP58
Cilia and flagella associated protein 58; Belongs to the CFAP58 family.
   
  
 0.628
THEGL
Testicular haploid expressed gene protein-like; Theg spermatid protein like.
      
 0.625
ATP6V1FNB
Protein ATP6V1FNB; ATP6V1F neighbor.
      
 0.622
NAA20
N-alpha-acetyltransferase 20; Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration; Belongs to the acetyltransferase family. ARD1 subfamily.
    
 
 0.595
CFAP43
Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.
   
  
 0.590
RSPH3
Radial spoke head protein 3 homolog; Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia. Belongs to the flagellar radial spoke RSP3 family.
   
  
 0.589
CRNKL1
Crooked neck-like protein 1; Involved in pre-mRNA splicing process. Belongs to the crooked-neck family.
      
 0.562
CFAP70
Cilia and flagella associated protein 70; Belongs to the CFAP70 family.
   
 
 0.544
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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