node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARSG | JPT2 | ENSP00000407193 | ENSP00000248098 | Arylsulfatase G; Displays arylsulfatase activity at acidic pH with pseudosubstrates, such as p-nitrocatechol sulfate and also, but with lower activity, p-nitrophenyl sulfate and 4-methylumbelliferyl sulfate. | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | 0.462 |
ASPDH | JPT2 | ENSP00000373860 | ENSP00000248098 | Putative L-aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | 0.475 |
CRAMP1 | JPT2 | ENSP00000380559 | ENSP00000248098 | Protein cramped-like; Cramped chromatin regulator homolog 1. | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | 0.567 |
EEF1AKNMT | JPT2 | ENSP00000354920 | ENSP00000248098 | eEF1A lysine and N-terminal methyltransferase; Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2) at two different positions, and is therefore involved in the regulation of mRNA translation. Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2'. Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55'. Has no activity towards core histones H2A, H2B, H3 and H4. | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | 0.461 |
JPT1 | JPT2 | ENSP00000348316 | ENSP00000248098 | Jupiter microtubule associated homolog 1, N-terminally processed; Modulates negatively AKT-mediated GSK3B signaling. Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions. Plays a role in the regulation of cell cycle and cell adhesion. Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation. Belongs to the JUPITER family. | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | 0.724 |
JPT1 | STMN1 | ENSP00000348316 | ENSP00000410452 | Jupiter microtubule associated homolog 1, N-terminally processed; Modulates negatively AKT-mediated GSK3B signaling. Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions. Plays a role in the regulation of cell cycle and cell adhesion. Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation. Belongs to the JUPITER family. | Stathmin; Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity); Belongs to the stathmin family. | 0.517 |
JPT2 | ARSG | ENSP00000248098 | ENSP00000407193 | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | Arylsulfatase G; Displays arylsulfatase activity at acidic pH with pseudosubstrates, such as p-nitrocatechol sulfate and also, but with lower activity, p-nitrophenyl sulfate and 4-methylumbelliferyl sulfate. | 0.462 |
JPT2 | ASPDH | ENSP00000248098 | ENSP00000373860 | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | Putative L-aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. | 0.475 |
JPT2 | CRAMP1 | ENSP00000248098 | ENSP00000380559 | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | Protein cramped-like; Cramped chromatin regulator homolog 1. | 0.567 |
JPT2 | EEF1AKNMT | ENSP00000248098 | ENSP00000354920 | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | eEF1A lysine and N-terminal methyltransferase; Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2) at two different positions, and is therefore involved in the regulation of mRNA translation. Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2'. Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55'. Has no activity towards core histones H2A, H2B, H3 and H4. | 0.461 |
JPT2 | JPT1 | ENSP00000248098 | ENSP00000348316 | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | Jupiter microtubule associated homolog 1, N-terminally processed; Modulates negatively AKT-mediated GSK3B signaling. Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions. Plays a role in the regulation of cell cycle and cell adhesion. Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation. Belongs to the JUPITER family. | 0.724 |
JPT2 | LSM12 | ENSP00000248098 | ENSP00000466718 | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | LSM12 homolog. | 0.650 |
JPT2 | STMN1 | ENSP00000248098 | ENSP00000410452 | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | Stathmin; Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity); Belongs to the stathmin family. | 0.455 |
JPT2 | TPCN1 | ENSP00000248098 | ENSP00000448083 | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | Two pore calcium channel protein 1; Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal and endosomal membrane. | 0.517 |
JPT2 | TPCN2 | ENSP00000248098 | ENSP00000294309 | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | Two pore calcium channel protein 2; Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal membrane. May be involved in smooth muscle contraction; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. Two pore calcium channel subfamily. | 0.586 |
JPT2 | YARS1 | ENSP00000248098 | ENSP00000362576 | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.484 |
LSM12 | JPT2 | ENSP00000466718 | ENSP00000248098 | LSM12 homolog. | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | 0.650 |
STMN1 | JPT1 | ENSP00000410452 | ENSP00000348316 | Stathmin; Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity); Belongs to the stathmin family. | Jupiter microtubule associated homolog 1, N-terminally processed; Modulates negatively AKT-mediated GSK3B signaling. Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions. Plays a role in the regulation of cell cycle and cell adhesion. Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation. Belongs to the JUPITER family. | 0.517 |
STMN1 | JPT2 | ENSP00000410452 | ENSP00000248098 | Stathmin; Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity); Belongs to the stathmin family. | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | 0.455 |
TPCN1 | JPT2 | ENSP00000448083 | ENSP00000248098 | Two pore calcium channel protein 1; Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal and endosomal membrane. | Jupiter microtubule associated homolog 2; Belongs to the JUPITER family. | 0.517 |