node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DYNLL2 | THAP10 | ENSP00000477310 | ENSP00000249861 | Dynein light chain 2, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity); Belongs to the dynein light chain family. | THAP domain containing 10. | 0.582 |
LRRC49 | THAP10 | ENSP00000453273 | ENSP00000249861 | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | THAP domain containing 10. | 0.687 |
THAP10 | DYNLL2 | ENSP00000249861 | ENSP00000477310 | THAP domain containing 10. | Dynein light chain 2, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity); Belongs to the dynein light chain family. | 0.582 |
THAP10 | LRRC49 | ENSP00000249861 | ENSP00000453273 | THAP domain containing 10. | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | 0.687 |
THAP10 | THAP12 | ENSP00000249861 | ENSP00000260045 | THAP domain containing 10. | 52 kDa repressor of the inhibitor of the protein kinase; Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth. | 0.593 |
THAP10 | THAP3 | ENSP00000249861 | ENSP00000054650 | THAP domain containing 10. | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | 0.570 |
THAP10 | THAP4 | ENSP00000249861 | ENSP00000385006 | THAP domain containing 10. | THAP domain containing 4. | 0.571 |
THAP10 | THAP5 | ENSP00000249861 | ENSP00000400500 | THAP domain containing 10. | THAP domain-containing protein 5; Has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro). May be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase. | 0.583 |
THAP10 | THAP6 | ENSP00000249861 | ENSP00000309007 | THAP domain containing 10. | THAP domain containing 6. | 0.611 |
THAP10 | THAP7 | ENSP00000249861 | ENSP00000215742 | THAP domain containing 10. | THAP domain-containing protein 7; Chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressors. | 0.573 |
THAP10 | THAP8 | ENSP00000249861 | ENSP00000292894 | THAP domain containing 10. | THAP domain containing 8. | 0.701 |
THAP10 | THAP9 | ENSP00000249861 | ENSP00000305533 | THAP domain containing 10. | DNA transposase THAP9; Active transposase that specifically recognizes the bipartite 5'-TXXGGGX(A/T)-3' consensus motif and mediates transposition. | 0.600 |
THAP12 | THAP10 | ENSP00000260045 | ENSP00000249861 | 52 kDa repressor of the inhibitor of the protein kinase; Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth. | THAP domain containing 10. | 0.593 |
THAP12 | THAP3 | ENSP00000260045 | ENSP00000054650 | 52 kDa repressor of the inhibitor of the protein kinase; Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth. | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | 0.882 |
THAP12 | THAP4 | ENSP00000260045 | ENSP00000385006 | 52 kDa repressor of the inhibitor of the protein kinase; Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth. | THAP domain containing 4. | 0.905 |
THAP12 | THAP5 | ENSP00000260045 | ENSP00000400500 | 52 kDa repressor of the inhibitor of the protein kinase; Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth. | THAP domain-containing protein 5; Has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro). May be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase. | 0.648 |
THAP12 | THAP6 | ENSP00000260045 | ENSP00000309007 | 52 kDa repressor of the inhibitor of the protein kinase; Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth. | THAP domain containing 6. | 0.480 |
THAP12 | THAP7 | ENSP00000260045 | ENSP00000215742 | 52 kDa repressor of the inhibitor of the protein kinase; Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth. | THAP domain-containing protein 7; Chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressors. | 0.912 |
THAP12 | THAP8 | ENSP00000260045 | ENSP00000292894 | 52 kDa repressor of the inhibitor of the protein kinase; Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth. | THAP domain containing 8. | 0.585 |
THAP12 | THAP9 | ENSP00000260045 | ENSP00000305533 | 52 kDa repressor of the inhibitor of the protein kinase; Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth. | DNA transposase THAP9; Active transposase that specifically recognizes the bipartite 5'-TXXGGGX(A/T)-3' consensus motif and mediates transposition. | 0.611 |