RPS4Y1 protein (human) - STRING interaction network

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RPS4Y1

Ribosomal protein S4 Y-linked 1; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa)

Predicted Functional Partners:

KDM5D

0.999

EIF1AY

0.999

FAU

0.999

RPS11

0.998

RPS3

0.998

RPS6

0.998

RPS9

0.998

RPS24

0.998

RPS23

0.997

RPS2

0.997

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF1AY	FAU	ENSP00000354722	ENSP00000431822	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	0.972
EIF1AY	KDM5D	ENSP00000354722	ENSP00000322408	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).	Lysine-specific demethylase 5D; Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. Involved in transcriptional repression of diverse metastasis-associated genes; in this function seems to cooperate with ZMYND8. Suppresses prostate cancer cell invasion. Regulates androgen receptor (AR) transcriptional activity [...]	0.999
EIF1AY	RPS11	ENSP00000354722	ENSP00000270625	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).	Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family.	0.981
EIF1AY	RPS2	ENSP00000354722	ENSP00000341885	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).	Ribosomal protein S2.	0.960
EIF1AY	RPS23	ENSP00000354722	ENSP00000296674	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).	40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]	0.964
EIF1AY	RPS24	ENSP00000354722	ENSP00000414321	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).	40S ribosomal protein S24; Required for processing of pre-rRNA and maturation of 40S ribosomal subunits; Belongs to the eukaryotic ribosomal protein eS24 family.	0.883
EIF1AY	RPS3	ENSP00000354722	ENSP00000278572	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).	40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro- 8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...]	0.978
EIF1AY	RPS4Y1	ENSP00000354722	ENSP00000250784	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).	Ribosomal protein S4 Y-linked 1; Belongs to the eukaryotic ribosomal protein eS4 family.	0.999
EIF1AY	RPS6	ENSP00000354722	ENSP00000369757	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).	40S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA; Belongs to the eukaryotic ribosomal protein eS6 family.	0.866
EIF1AY	RPS9	ENSP00000354722	ENSP00000375632	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).	Ribosomal protein S9.	0.954
FAU	EIF1AY	ENSP00000431822	ENSP00000354722	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).	0.972
FAU	RPS11	ENSP00000431822	ENSP00000270625	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family.	0.999
FAU	RPS2	ENSP00000431822	ENSP00000341885	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein S2.	0.999
FAU	RPS23	ENSP00000431822	ENSP00000296674	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]	0.999
FAU	RPS24	ENSP00000431822	ENSP00000414321	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	40S ribosomal protein S24; Required for processing of pre-rRNA and maturation of 40S ribosomal subunits; Belongs to the eukaryotic ribosomal protein eS24 family.	0.999
FAU	RPS3	ENSP00000431822	ENSP00000278572	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro- 8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...]	0.999
FAU	RPS4Y1	ENSP00000431822	ENSP00000250784	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein S4 Y-linked 1; Belongs to the eukaryotic ribosomal protein eS4 family.	0.999
FAU	RPS6	ENSP00000431822	ENSP00000369757	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	40S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA; Belongs to the eukaryotic ribosomal protein eS6 family.	0.999
FAU	RPS9	ENSP00000431822	ENSP00000375632	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein S9.	0.999
KDM5D	EIF1AY	ENSP00000322408	ENSP00000354722	Lysine-specific demethylase 5D; Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. Involved in transcriptional repression of diverse metastasis-associated genes; in this function seems to cooperate with ZMYND8. Suppresses prostate cancer cell invasion. Regulates androgen receptor (AR) transcriptional activity [...]	Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).	0.999