TUBG1 protein (human) - STRING interaction network

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TUBG1

Tubulin gamma-1 chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation. (451 aa)

Predicted Functional Partners:

TUBGCP6

0.999

TUBG2

0.999

TUBGCP4

0.999

TUBGCP3

0.999

MZT2A

0.999

MZT1

0.999

MZT2B

0.999

BRCA1

0.999

TUBGCP2

0.999

NEDD1

0.999

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRCA1	MZT1	ENSP00000418960	ENSP00000367049	Breast cancer type 1 susceptibility protein; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic [...]	Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome; Belongs to the MOZART1 family.	0.903
BRCA1	MZT2A	ENSP00000418960	ENSP00000311500	Breast cancer type 1 susceptibility protein; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic [...]	Mitotic spindle organizing protein 2A; Belongs to the MOZART2 family.	0.900
BRCA1	TUBG1	ENSP00000418960	ENSP00000251413	Breast cancer type 1 susceptibility protein; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic [...]	Tubulin gamma-1 chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.	0.999
BRCA1	TUBG2	ENSP00000418960	ENSP00000251412	Breast cancer type 1 susceptibility protein; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic [...]	Tubulin gamma-2 chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity).	0.904
BRCA1	TUBGCP2	ENSP00000418960	ENSP00000446093	Breast cancer type 1 susceptibility protein; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic [...]	Gamma-tubulin complex component 2; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.	0.744
BRCA1	TUBGCP3	ENSP00000418960	ENSP00000261965	Breast cancer type 1 susceptibility protein; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic [...]	Gamma-tubulin complex component 3; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.	0.744
BRCA1	TUBGCP4	ENSP00000418960	ENSP00000260383	Breast cancer type 1 susceptibility protein; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic [...]	Gamma-tubulin complex component 4; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.	0.908
BRCA1	TUBGCP6	ENSP00000418960	ENSP00000248846	Breast cancer type 1 susceptibility protein; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic [...]	Gamma-tubulin complex component 6; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.	0.907
MZT1	BRCA1	ENSP00000367049	ENSP00000418960	Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome; Belongs to the MOZART1 family.	Breast cancer type 1 susceptibility protein; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic [...]	0.903
MZT1	MZT2A	ENSP00000367049	ENSP00000311500	Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome; Belongs to the MOZART1 family.	Mitotic spindle organizing protein 2A; Belongs to the MOZART2 family.	0.999
MZT1	MZT2B	ENSP00000367049	ENSP00000386419	Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome; Belongs to the MOZART1 family.	Mitotic spindle organizing protein 2B.	0.999
MZT1	NEDD1	ENSP00000367049	ENSP00000451211	Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome; Belongs to the MOZART1 family.	Protein NEDD1; Required for mitosis progression. Promotes the nucleation of microtubules from the spindle.	0.995
MZT1	TUBG1	ENSP00000367049	ENSP00000251413	Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome; Belongs to the MOZART1 family.	Tubulin gamma-1 chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.	0.999
MZT1	TUBG2	ENSP00000367049	ENSP00000251412	Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome; Belongs to the MOZART1 family.	Tubulin gamma-2 chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity).	0.939
MZT1	TUBGCP2	ENSP00000367049	ENSP00000446093	Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome; Belongs to the MOZART1 family.	Gamma-tubulin complex component 2; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.	0.999
MZT1	TUBGCP3	ENSP00000367049	ENSP00000261965	Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome; Belongs to the MOZART1 family.	Gamma-tubulin complex component 3; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.	0.999
MZT1	TUBGCP4	ENSP00000367049	ENSP00000260383	Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome; Belongs to the MOZART1 family.	Gamma-tubulin complex component 4; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.	0.999
MZT1	TUBGCP6	ENSP00000367049	ENSP00000248846	Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome; Belongs to the MOZART1 family.	Gamma-tubulin complex component 6; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.	0.999
MZT2A	BRCA1	ENSP00000311500	ENSP00000418960	Mitotic spindle organizing protein 2A; Belongs to the MOZART2 family.	Breast cancer type 1 susceptibility protein; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic [...]	0.900
MZT2A	MZT1	ENSP00000311500	ENSP00000367049	Mitotic spindle organizing protein 2A; Belongs to the MOZART2 family.	Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome; Belongs to the MOZART1 family.	0.999

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