USHBP1 protein (human) - STRING interaction network

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Score

USHBP1

Usher syndrome type-1C protein-binding protein 1; USH1 protein network component harmonin binding protein 1. (703 aa)

Predicted Functional Partners:

MCCC2

0.960

USH1C

0.926

BTD

0.812

MMRN2

0.754

MCCC1

0.603

SERTAD3

0.539

ZMAT4

0.534

GMCL1

0.520

ZBTB25

0.503

ADGRF5

0.481

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRF5	MMRN2	ENSP00000283296	ENSP00000361097	Adhesion G protein-coupled receptor F5; Receptor that plays a critical role in lung surfactant homeostasis. May play a role in controlling adipocyte function. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.	Multimerin-2; Inhibits endothelial cells motility and acts as a negative regulator of angiogenesis; it downregulates KDR activation by binding VEGFA.	0.581
ADGRF5	USHBP1	ENSP00000283296	ENSP00000252597	Adhesion G protein-coupled receptor F5; Receptor that plays a critical role in lung surfactant homeostasis. May play a role in controlling adipocyte function. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.	Usher syndrome type-1C protein-binding protein 1; USH1 protein network component harmonin binding protein 1.	0.481
BTD	MCCC1	ENSP00000500193	ENSP00000265594	Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation.	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.	0.788
BTD	MCCC2	ENSP00000500193	ENSP00000343657	Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation.	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family.	0.814
BTD	USHBP1	ENSP00000500193	ENSP00000252597	Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation.	Usher syndrome type-1C protein-binding protein 1; USH1 protein network component harmonin binding protein 1.	0.812
GMCL1	USHBP1	ENSP00000282570	ENSP00000252597	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	Usher syndrome type-1C protein-binding protein 1; USH1 protein network component harmonin binding protein 1.	0.520
GMCL1	ZBTB25	ENSP00000282570	ENSP00000476746	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	Zinc finger and BTB domain-containing protein 25; May be involved in transcriptional regulation.	0.411
MCCC1	BTD	ENSP00000265594	ENSP00000500193	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.	Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation.	0.788
MCCC1	MCCC2	ENSP00000265594	ENSP00000343657	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family.	0.999
MCCC1	USHBP1	ENSP00000265594	ENSP00000252597	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.	Usher syndrome type-1C protein-binding protein 1; USH1 protein network component harmonin binding protein 1.	0.603
MCCC2	BTD	ENSP00000343657	ENSP00000500193	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family.	Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation.	0.814
MCCC2	MCCC1	ENSP00000343657	ENSP00000265594	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family.	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.	0.999
MCCC2	USHBP1	ENSP00000343657	ENSP00000252597	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family.	Usher syndrome type-1C protein-binding protein 1; USH1 protein network component harmonin binding protein 1.	0.960
MMRN2	ADGRF5	ENSP00000361097	ENSP00000283296	Multimerin-2; Inhibits endothelial cells motility and acts as a negative regulator of angiogenesis; it downregulates KDR activation by binding VEGFA.	Adhesion G protein-coupled receptor F5; Receptor that plays a critical role in lung surfactant homeostasis. May play a role in controlling adipocyte function. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.	0.581
MMRN2	USHBP1	ENSP00000361097	ENSP00000252597	Multimerin-2; Inhibits endothelial cells motility and acts as a negative regulator of angiogenesis; it downregulates KDR activation by binding VEGFA.	Usher syndrome type-1C protein-binding protein 1; USH1 protein network component harmonin binding protein 1.	0.754
SERTAD3	USHBP1	ENSP00000375882	ENSP00000252597	SERTA domain-containing protein 3; Strong transcriptional coactivator.	Usher syndrome type-1C protein-binding protein 1; USH1 protein network component harmonin binding protein 1.	0.539
USH1C	USHBP1	ENSP00000005226	ENSP00000252597	Harmonin; USH1 protein network component harmonin.	Usher syndrome type-1C protein-binding protein 1; USH1 protein network component harmonin binding protein 1.	0.926
USHBP1	ADGRF5	ENSP00000252597	ENSP00000283296	Usher syndrome type-1C protein-binding protein 1; USH1 protein network component harmonin binding protein 1.	Adhesion G protein-coupled receptor F5; Receptor that plays a critical role in lung surfactant homeostasis. May play a role in controlling adipocyte function. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.	0.481
USHBP1	BTD	ENSP00000252597	ENSP00000500193	Usher syndrome type-1C protein-binding protein 1; USH1 protein network component harmonin binding protein 1.	Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation.	0.812
USHBP1	GMCL1	ENSP00000252597	ENSP00000282570	Usher syndrome type-1C protein-binding protein 1; USH1 protein network component harmonin binding protein 1.	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	0.520