STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YIPF2Protein YIPF2; Yip1 domain family member 2 (316 aa)    
Predicted Functional Partners:
YIPF6
Protein YIPF6; May be required for stable YIPF1 and YIPF2 protein expression; Yip1 domain containing
   
 
 0.973
YIPF5
Protein YIPF5; Plays a role in transport between endoplasmic reticulum and Golgi; Yip1 domain containing
   
 
 0.946
YIPF3
Protein YIPF3; Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis; Yip1 domain containing
   
  
 0.928
YIPF4
Protein YIPF4; Involved in the maintenance of the Golgi structure; Belongs to the YIP1 family
   
 
 0.843
SLC38A7
Putative sodium-coupled neutral amino acid transporter 7; Mediates sodium-dependent transport of amino acids, preferentially L-glutamine; Belongs to the amino acid/polyamine transporter 2 family
   
  
 0.692
SLC39A7
Zinc transporter SLC39A7; Zinc transporter, that transports Zn(2+) from the endoplasmic reticulum/Golgi apparatus to the cytosol. Transport is stimulated by growth factors, such as EGF, and Ca(2+), as well as by exogenous Zn(2+); Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily
   
 
 0.689
MORC2
MORC family CW-type zinc finger protein 2; Exhibits a cytosolic function in lipogenesis, adipogenic differentiation, and lipid homeostasis by increasing the activity of ACLY, possibly preventing its dephosphorylation. May act as a transcriptional repressor. Down-regulates CA9 expression; Zinc fingers CW-type
      
 0.684
YIPF7
Protein YIPF7; Yip1 domain family member 7; Belongs to the YIP1 family
   
 
 0.674
ICT1
Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes
   
  
 0.649
ZBTB24
Zinc finger and BTB domain-containing protein 24; May be involved in BMP2-induced transcription; BTB domain containing
      
 0.605
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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