STRINGSTRING
VRTN protein (human) - STRING interaction network
"VRTN" - Vertnin in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VRTNVertnin; Vertebrae development associated; Belongs to the vertnin family (702 aa)    
Predicted Functional Partners:
PROX2
Prospero homeobox protein 2; Transcription regulator. Does not seem to be essential for embryonic development and postnatal survival (By similarity); Belongs to the Prospero homeodomain family (592 aa)
           
  0.753
SYNDIG1L
Synapse differentiation-inducing gene protein 1-like; Interferon induced transmembrane protein domain containing (238 aa)
           
  0.753
ARMC4
Armadillo repeat-containing protein 4; Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly; Armadillo repeat containing (1044 aa)
           
  0.675
LRRC74A
Leucine-rich repeat-containing protein 74A; Leucine rich repeat containing 74A (488 aa)
           
  0.669
SYNDIG1
Synapse differentiation-inducing gene protein 1; May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation; Belongs to the CD225/Dispanin family (258 aa)
           
  0.657
NR6A1
Nuclear receptor subfamily 6 group A member 1; Orphan nuclear receptor. Binds to a response element containing the sequence 5’-TCAAGGTCA-3’. May be involved in the regulation of gene expression in germ cell development during gametogenesis (By similarity); Nuclear hormone receptors (480 aa)
     
   
  0.656
ZNF614
Zinc finger protein 614; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (585 aa)
           
  0.597
AREL1
Apoptosis-resistant E3 ubiquitin protein ligase 1; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits apoptosis by ubiquitinating and targeting for degradation a number of proapoptotic proteins including DIABLO/SMAC, HTRA2 and SEPT4/ARTS which are released from the mitochondrion into the cytosol following apoptotic stimulation (823 aa)
           
  0.574
L1TD1
LINE1 type transposase domain containing 1; Belongs to the transposase 22 family (865 aa)
     
   
  0.527
LIN28A
Protein lin-28 homolog A; RNA-binding protein that inhibits processing of pre-let- 7 miRNAs and regulates translation of mRNAs that control developmental timing, pluripotency and metabolism. Seems to recognize a common structural G- quartet (G4) feature in its miRNA and mRNA targets (Probable). ’Translational enhancer’ that drives specific mRNAs to polysomes and increases the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in mRNA stabilization. B [...] (209 aa)
     
   
  0.523
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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