STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EMC7ER membrane protein complex subunit 7 (242 aa)    
Predicted Functional Partners:
EMC4
ER membrane protein complex subunit 4; May mediate anti-apoptotic activity
   
 0.999
MMGT1
Membrane magnesium transporter 1; Mediates Mg(2+) transport; Belongs to the membrane magnesium transporter (TC 1.A.67) family
   
 0.999
EMC10
ER membrane protein complex subunit 10; Belongs to the EMC10 family
   
 0.999
EMC2
ER membrane protein complex subunit 2; Tetratricopeptide repeat domain containing
   
 0.998
EMC3
ER membrane protein complex subunit 3
   
 0.998
EMC8
ER membrane protein complex subunit 8
   
 0.998
EMC9
ER membrane protein complex subunit 9
   
 0.998
EMC1
ER membrane protein complex subunit 1; Belongs to the EMC1 family
   
 0.998
EMC6
ER membrane protein complex subunit 6; Belongs to the EMC6 family
   
 0.996
CHMP2A
Charged multivesicular body protein 2a; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential functio [...]
   
  
 0.830
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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