STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM60Transmembrane protein 60. (133 aa)    
Predicted Functional Partners:
TVP23B
Trans-golgi network vesicle protein 23 homolog B; Belongs to the TVP23 family.
   
  
 0.689
FAM229B
Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family.
      
 0.569
WDR37
WD repeat domain 37.
      
 0.558
TMEM120A
Transmembrane protein 120A; Necessary for efficient adipogenesis. Belongs to the TMEM120 family.
   
  
 0.513
WDR72
WD repeat-containing protein 72; Plays a major role in formation of tooth enamel. Specifically required during the maturation phase of amelogenesis for normal formation of the enamel matrix and clearance of enamel proteins. May be involved in localization of the calcium transporter SLC24A4 to the ameloblast cell membrane.
      
 0.504
TMEM120B
Transmembrane protein 120B; Necessary for efficient adipogenesis. Belongs to the TMEM120 family.
      
 0.494
ANXA9
Annexin A9; Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes. Belongs to the annexin family.
      
 0.480
TMEM203
Transmembrane protein 203; Involved in the regulation of cellular calcium homeotasis. Required for spermatogenesis.
   
 
 0.477
SFT2D1
Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family.
   
  
 0.452
SLC6A13
Sodium- and chloride-dependent GABA transporter 2; Sodium-dependent GABA and taurine transporter. In presynaptic terminals, regulates GABA signaling termination through GABA uptake. May also be involved in beta-alanine transport.
      
 0.448
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.