node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC102A | CCDC102B | ENSP00000258214 | ENSP00000353377 | Coiled-coil domain containing 102A. | Coiled-coil domain containing 102B. | 0.518 |
CCDC102A | CDC42EP4 | ENSP00000258214 | ENSP00000338258 | Coiled-coil domain containing 102A. | Cdc42 effector protein 4; Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts; Belongs to the BORG/CEP family. | 0.498 |
CCDC102A | DOK4 | ENSP00000258214 | ENSP00000455566 | Coiled-coil domain containing 102A. | Docking protein 4; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells. | 0.502 |
CCDC102A | ERLEC1 | ENSP00000258214 | ENSP00000185150 | Coiled-coil domain containing 102A. | Endoplasmic reticulum lectin 1; Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non- glycosylated proteins and glycoproteins. | 0.458 |
CCDC102A | FAM207A | ENSP00000258214 | ENSP00000291634 | Coiled-coil domain containing 102A. | Protein FAM207A; Family with sequence similarity 207 member A. | 0.460 |
CCDC102A | GALNT16 | ENSP00000258214 | ENSP00000336729 | Coiled-coil domain containing 102A. | Polypeptide N-acetylgalactosaminyltransferase 16; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. | 0.492 |
CCDC102A | HEG1 | ENSP00000258214 | ENSP00000311502 | Coiled-coil domain containing 102A. | Protein HEG homolog 1; Receptor component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity May act through the stabilization of endothelial cell junctions. | 0.470 |
CCDC102A | KIAA1671 | ENSP00000258214 | ENSP00000351207 | Coiled-coil domain containing 102A. | Uncharacterized protein KIAA1671; KIAA1671. | 0.534 |
CCDC102A | KTN1 | ENSP00000258214 | ENSP00000378725 | Coiled-coil domain containing 102A. | Kinectin; Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin; Belongs to the kinectin family. | 0.460 |
CCDC102A | SUGCT | ENSP00000258214 | ENSP00000486291 | Coiled-coil domain containing 102A. | Succinate--hydroxymethylglutarate CoA-transferase; Catalyzes the succinyl-CoA-dependent conversion of glutarate to glutaryl-CoA. Can use different dicarboxylic acids as CoA acceptors, the preferred ones are glutarate, succinate, adipate, and 3- hydroxymethylglutarate; Belongs to the CoA-transferase III family. | 0.461 |
CCDC102B | CCDC102A | ENSP00000353377 | ENSP00000258214 | Coiled-coil domain containing 102B. | Coiled-coil domain containing 102A. | 0.518 |
CDC42EP4 | CCDC102A | ENSP00000338258 | ENSP00000258214 | Cdc42 effector protein 4; Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts; Belongs to the BORG/CEP family. | Coiled-coil domain containing 102A. | 0.498 |
DOK4 | CCDC102A | ENSP00000455566 | ENSP00000258214 | Docking protein 4; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells. | Coiled-coil domain containing 102A. | 0.502 |
ERLEC1 | CCDC102A | ENSP00000185150 | ENSP00000258214 | Endoplasmic reticulum lectin 1; Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non- glycosylated proteins and glycoproteins. | Coiled-coil domain containing 102A. | 0.458 |
FAM207A | CCDC102A | ENSP00000291634 | ENSP00000258214 | Protein FAM207A; Family with sequence similarity 207 member A. | Coiled-coil domain containing 102A. | 0.460 |
GALNT16 | CCDC102A | ENSP00000336729 | ENSP00000258214 | Polypeptide N-acetylgalactosaminyltransferase 16; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. | Coiled-coil domain containing 102A. | 0.492 |
GALNT16 | KIAA1671 | ENSP00000336729 | ENSP00000351207 | Polypeptide N-acetylgalactosaminyltransferase 16; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. | Uncharacterized protein KIAA1671; KIAA1671. | 0.476 |
HEG1 | CCDC102A | ENSP00000311502 | ENSP00000258214 | Protein HEG homolog 1; Receptor component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity May act through the stabilization of endothelial cell junctions. | Coiled-coil domain containing 102A. | 0.470 |
HEG1 | KTN1 | ENSP00000311502 | ENSP00000378725 | Protein HEG homolog 1; Receptor component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity May act through the stabilization of endothelial cell junctions. | Kinectin; Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin; Belongs to the kinectin family. | 0.402 |
KIAA1671 | CCDC102A | ENSP00000351207 | ENSP00000258214 | Uncharacterized protein KIAA1671; KIAA1671. | Coiled-coil domain containing 102A. | 0.534 |