node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C12orf29 | SLCO5A1 | ENSP00000349358 | ENSP00000260126 | Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29. | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | 0.477 |
CATSPERE | SLCO5A1 | ENSP00000355492 | ENSP00000260126 | Cation channel sperm-associated protein subunit epsilon; Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization; Belongs to the CATSPERD family. | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | 0.488 |
RAB31 | SLCO5A1 | ENSP00000461945 | ENSP00000260126 | Ras-related protein Rab-31; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Pl [...] | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | 0.405 |
RNF217 | SLCO5A1 | ENSP00000428698 | ENSP00000260126 | Probable E3 ubiquitin-protein ligase RNF217; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates; Belongs to the RBR family. RNF217 subfamily. | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | 0.452 |
SHOX | SLCO5A1 | ENSP00000370990 | ENSP00000260126 | Short stature homeobox protein; Controls fundamental aspects of growth and development; Belongs to the paired homeobox family. Bicoid subfamily. | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | 0.458 |
SLC22A14 | SLCO5A1 | ENSP00000273173 | ENSP00000260126 | Solute carrier family 22 member 14; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | 0.400 |
SLCO3A1 | SLCO5A1 | ENSP00000320634 | ENSP00000260126 | Solute carrier organic anion transporter family member 3A1; Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3-sulfate, taurocholate, digoxin nor DHEAS. | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | 0.428 |
SLCO5A1 | C12orf29 | ENSP00000260126 | ENSP00000349358 | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29. | 0.477 |
SLCO5A1 | CATSPERE | ENSP00000260126 | ENSP00000355492 | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | Cation channel sperm-associated protein subunit epsilon; Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization; Belongs to the CATSPERD family. | 0.488 |
SLCO5A1 | RAB31 | ENSP00000260126 | ENSP00000461945 | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | Ras-related protein Rab-31; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Pl [...] | 0.405 |
SLCO5A1 | RNF217 | ENSP00000260126 | ENSP00000428698 | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | Probable E3 ubiquitin-protein ligase RNF217; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates; Belongs to the RBR family. RNF217 subfamily. | 0.452 |
SLCO5A1 | SHOX | ENSP00000260126 | ENSP00000370990 | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | Short stature homeobox protein; Controls fundamental aspects of growth and development; Belongs to the paired homeobox family. Bicoid subfamily. | 0.458 |
SLCO5A1 | SLC22A14 | ENSP00000260126 | ENSP00000273173 | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | Solute carrier family 22 member 14; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. | 0.400 |
SLCO5A1 | SLCO3A1 | ENSP00000260126 | ENSP00000320634 | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | Solute carrier organic anion transporter family member 3A1; Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3-sulfate, taurocholate, digoxin nor DHEAS. | 0.428 |
SLCO5A1 | SULF1 | ENSP00000260126 | ENSP00000260128 | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | Extracellular sulfatase Sulf-1; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Diminishes HSPG (heparan sulfate proteoglycans) sulfation, inhibits signaling by heparin-dependent growth factors, diminishes proliferation, and facilitates apoptosis in response to exogenous stimulation. | 0.925 |
SLCO5A1 | SULF2 | ENSP00000260126 | ENSP00000353007 | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | Extracellular sulfatase Sulf-2; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin; Belongs to the sulfatase family. | 0.499 |
SULF1 | SLCO5A1 | ENSP00000260128 | ENSP00000260126 | Extracellular sulfatase Sulf-1; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Diminishes HSPG (heparan sulfate proteoglycans) sulfation, inhibits signaling by heparin-dependent growth factors, diminishes proliferation, and facilitates apoptosis in response to exogenous stimulation. | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | 0.925 |
SULF2 | SLCO5A1 | ENSP00000353007 | ENSP00000260126 | Extracellular sulfatase Sulf-2; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin; Belongs to the sulfatase family. | Solute carrier organic anion transporter family member 5A1; Belongs to the organo anion transporter (TC 2.A.60) family. | 0.499 |