node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CTDSPL2 | GAS2L1 | ENSP00000260327 | ENSP00000481012 | CTD small phosphatase-like protein 2; Probable phosphatase. | GAS2-like protein 1; Involved in the cross-linking of microtubules and microfilaments. Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers. Belongs to the GAS2 family. | 0.477 |
CTDSPL2 | GTF2F1 | ENSP00000260327 | ENSP00000377969 | CTD small phosphatase-like protein 2; Probable phosphatase. | General transcription factor IIF subunit 1; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. | 0.632 |
CTDSPL2 | KLHDC1 | ENSP00000260327 | ENSP00000352282 | CTD small phosphatase-like protein 2; Probable phosphatase. | Kelch domain containing 1. | 0.533 |
CTDSPL2 | KPNA1 | ENSP00000260327 | ENSP00000343701 | CTD small phosphatase-like protein 2; Probable phosphatase. | Importin subunit alpha-5, N-terminally processed; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and impo [...] | 0.476 |
CTDSPL2 | KPNA2 | ENSP00000260327 | ENSP00000438483 | CTD small phosphatase-like protein 2; Probable phosphatase. | Importin subunit alpha-1; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...] | 0.604 |
CTDSPL2 | KPNA3 | ENSP00000260327 | ENSP00000261667 | CTD small phosphatase-like protein 2; Probable phosphatase. | Importin subunit alpha-4; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...] | 0.500 |
CTDSPL2 | KPNA4 | ENSP00000260327 | ENSP00000334373 | CTD small phosphatase-like protein 2; Probable phosphatase. | Importin subunit alpha-3; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...] | 0.614 |
CTDSPL2 | PDIK1L | ENSP00000260327 | ENSP00000363389 | CTD small phosphatase-like protein 2; Probable phosphatase. | Serine/threonine-protein kinase PDIK1L; PDLIM1 interacting kinase 1 like. | 0.872 |
CTDSPL2 | STK35 | ENSP00000260327 | ENSP00000370891 | CTD small phosphatase-like protein 2; Probable phosphatase. | Serine/threonine kinase 35. | 0.699 |
CTDSPL2 | UBLCP1 | ENSP00000260327 | ENSP00000296786 | CTD small phosphatase-like protein 2; Probable phosphatase. | Ubiquitin-like domain-containing CTD phosphatase 1; Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome. | 0.520 |
GAS2L1 | CTDSPL2 | ENSP00000481012 | ENSP00000260327 | GAS2-like protein 1; Involved in the cross-linking of microtubules and microfilaments. Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers. Belongs to the GAS2 family. | CTD small phosphatase-like protein 2; Probable phosphatase. | 0.477 |
GAS2L1 | KLHDC1 | ENSP00000481012 | ENSP00000352282 | GAS2-like protein 1; Involved in the cross-linking of microtubules and microfilaments. Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers. Belongs to the GAS2 family. | Kelch domain containing 1. | 0.502 |
GTF2F1 | CTDSPL2 | ENSP00000377969 | ENSP00000260327 | General transcription factor IIF subunit 1; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. | CTD small phosphatase-like protein 2; Probable phosphatase. | 0.632 |
GTF2F1 | UBLCP1 | ENSP00000377969 | ENSP00000296786 | General transcription factor IIF subunit 1; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. | Ubiquitin-like domain-containing CTD phosphatase 1; Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome. | 0.667 |
KLHDC1 | CTDSPL2 | ENSP00000352282 | ENSP00000260327 | Kelch domain containing 1. | CTD small phosphatase-like protein 2; Probable phosphatase. | 0.533 |
KLHDC1 | GAS2L1 | ENSP00000352282 | ENSP00000481012 | Kelch domain containing 1. | GAS2-like protein 1; Involved in the cross-linking of microtubules and microfilaments. Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers. Belongs to the GAS2 family. | 0.502 |
KPNA1 | CTDSPL2 | ENSP00000343701 | ENSP00000260327 | Importin subunit alpha-5, N-terminally processed; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and impo [...] | CTD small phosphatase-like protein 2; Probable phosphatase. | 0.476 |
KPNA1 | KPNA2 | ENSP00000343701 | ENSP00000438483 | Importin subunit alpha-5, N-terminally processed; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and impo [...] | Importin subunit alpha-1; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...] | 0.700 |
KPNA1 | KPNA3 | ENSP00000343701 | ENSP00000261667 | Importin subunit alpha-5, N-terminally processed; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and impo [...] | Importin subunit alpha-4; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...] | 0.946 |
KPNA1 | KPNA4 | ENSP00000343701 | ENSP00000334373 | Importin subunit alpha-5, N-terminally processed; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and impo [...] | Importin subunit alpha-3; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are [...] | 0.963 |