node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C9orf116 | CFAP161 | ENSP00000395281 | ENSP00000286732 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | 0.878 |
C9orf116 | CFAP53 | ENSP00000395281 | ENSP00000381553 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis. | 0.882 |
C9orf116 | EFHB | ENSP00000395281 | ENSP00000295824 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | EF-hand domain-containing family member B; Cytosolic sensor for calcium, modulates the interaction of STIM1 and ORAI1 upon store depletion, the activation of store-operated Ca(2+) entry (SOCE) and NFAT translocation from cytosol to nucleus. | 0.835 |
C9orf116 | EFHC1 | ENSP00000395281 | ENSP00000360107 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. | 0.854 |
C9orf116 | EFHC2 | ENSP00000395281 | ENSP00000404232 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | EF-hand domain-containing family member C2; EF-hand domain containing 2. | 0.875 |
C9orf116 | FAM166B | ENSP00000395281 | ENSP00000382646 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | Protein FAM166B; Family with sequence similarity 166 member B; Belongs to the UPF0605 family. | 0.866 |
C9orf116 | MNS1 | ENSP00000395281 | ENSP00000260453 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | Meiosis-specific nuclear structural protein 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis; Belongs to the MNS1 family. | 0.874 |
C9orf116 | PACRG | ENSP00000395281 | ENSP00000337946 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | Parkin coregulated gene protein; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease. | 0.844 |
C9orf116 | RIBC2 | ENSP00000395281 | ENSP00000483356 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | RIB43A domain with coiled-coils 2. | 0.846 |
C9orf116 | TEKT1 | ENSP00000395281 | ENSP00000341346 | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules; Belongs to the tektin family. | 0.942 |
CFAP161 | C9orf116 | ENSP00000286732 | ENSP00000395281 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. | 0.878 |
CFAP161 | CFAP53 | ENSP00000286732 | ENSP00000381553 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis. | 0.853 |
CFAP161 | EFHB | ENSP00000286732 | ENSP00000295824 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | EF-hand domain-containing family member B; Cytosolic sensor for calcium, modulates the interaction of STIM1 and ORAI1 upon store depletion, the activation of store-operated Ca(2+) entry (SOCE) and NFAT translocation from cytosol to nucleus. | 0.829 |
CFAP161 | EFHC1 | ENSP00000286732 | ENSP00000360107 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. | 0.885 |
CFAP161 | EFHC2 | ENSP00000286732 | ENSP00000404232 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | EF-hand domain-containing family member C2; EF-hand domain containing 2. | 0.915 |
CFAP161 | FAM166B | ENSP00000286732 | ENSP00000382646 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Protein FAM166B; Family with sequence similarity 166 member B; Belongs to the UPF0605 family. | 0.870 |
CFAP161 | MNS1 | ENSP00000286732 | ENSP00000260453 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Meiosis-specific nuclear structural protein 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis; Belongs to the MNS1 family. | 0.873 |
CFAP161 | PACRG | ENSP00000286732 | ENSP00000337946 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Parkin coregulated gene protein; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease. | 0.825 |
CFAP161 | RIBC2 | ENSP00000286732 | ENSP00000483356 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | RIB43A domain with coiled-coils 2. | 0.837 |
CFAP161 | TEKT1 | ENSP00000286732 | ENSP00000341346 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules; Belongs to the tektin family. | 0.876 |