node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C1orf109 | CALHM2 | ENSP00000350704 | ENSP00000260743 | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. | 0.612 |
C1orf109 | CWC25 | ENSP00000350704 | ENSP00000478070 | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | Pre-mRNA-splicing factor CWC25 homolog; Involved in pre-mRNA splicing as component of the spliceosome; Belongs to the CWC25 family. | 0.788 |
C1orf109 | FBXO47 | ENSP00000350704 | ENSP00000367319 | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | 0.601 |
C1orf109 | LINGO3 | ENSP00000350704 | ENSP00000467753 | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3; Leucine rich repeat and Ig domain containing 3. | 0.604 |
C1orf109 | LIX1 | ENSP00000350704 | ENSP00000274382 | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | Protein limb expression 1 homolog; Limb and CNS expressed 1; Belongs to the LIX1 family. | 0.788 |
C1orf109 | PGM2 | ENSP00000350704 | ENSP00000371393 | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | Phosphoglucomutase-2; Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5- phosphopentoses. May also catalyze the interconversion of glucose-1- phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity; Belongs to the phosphohexose mutase family. | 0.772 |
C1orf109 | RUBCNL | ENSP00000350704 | ENSP00000396935 | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | Protein associated with UVRAG as autophagy enhancer; Regulator of autophagy that promotes autophagosome maturation by facilitating the biogenesis of phosphatidylinositol 3-phosphate (PtdIns(3)P) in late steps of autophagy. Acts by antagonizing RUBCN, thereby stimulating phosphatidylinositol 3-kinase activity of the PI3K/PI3KC3 complex. Following anchorage to the autophagosomal SNARE STX17, promotes the recruitment of PI3K/PI3KC3 and HOPS complexes to the autophagosome to regulate the fusion specificity of autophagosomes with late endosomes/lysosomes. Binds phosphoinositides phosphatidy [...] | 0.788 |
C1orf109 | SLCO1A2 | ENSP00000350704 | ENSP00000305974 | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | Solute carrier organic anion transporter family member 1A2; Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin. | 0.788 |
C1orf109 | UGT3A1 | ENSP00000350704 | ENSP00000274278 | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | UDP-glucuronosyltransferase 3A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family. | 0.612 |
C1orf109 | UGT3A2 | ENSP00000350704 | ENSP00000282507 | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | UDP-glucuronosyltransferase 3A2; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family. | 0.612 |
CALHM2 | C1orf109 | ENSP00000260743 | ENSP00000350704 | Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | 0.612 |
CALHM2 | CWC25 | ENSP00000260743 | ENSP00000478070 | Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. | Pre-mRNA-splicing factor CWC25 homolog; Involved in pre-mRNA splicing as component of the spliceosome; Belongs to the CWC25 family. | 0.549 |
CALHM2 | FBXO47 | ENSP00000260743 | ENSP00000367319 | Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | 0.527 |
CALHM2 | LINGO3 | ENSP00000260743 | ENSP00000467753 | Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3; Leucine rich repeat and Ig domain containing 3. | 0.538 |
CALHM2 | LIX1 | ENSP00000260743 | ENSP00000274382 | Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. | Protein limb expression 1 homolog; Limb and CNS expressed 1; Belongs to the LIX1 family. | 0.586 |
CALHM2 | PGM2 | ENSP00000260743 | ENSP00000371393 | Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. | Phosphoglucomutase-2; Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5- phosphopentoses. May also catalyze the interconversion of glucose-1- phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity; Belongs to the phosphohexose mutase family. | 0.523 |
CALHM2 | RUBCNL | ENSP00000260743 | ENSP00000396935 | Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. | Protein associated with UVRAG as autophagy enhancer; Regulator of autophagy that promotes autophagosome maturation by facilitating the biogenesis of phosphatidylinositol 3-phosphate (PtdIns(3)P) in late steps of autophagy. Acts by antagonizing RUBCN, thereby stimulating phosphatidylinositol 3-kinase activity of the PI3K/PI3KC3 complex. Following anchorage to the autophagosomal SNARE STX17, promotes the recruitment of PI3K/PI3KC3 and HOPS complexes to the autophagosome to regulate the fusion specificity of autophagosomes with late endosomes/lysosomes. Binds phosphoinositides phosphatidy [...] | 0.574 |
CALHM2 | SLCO1A2 | ENSP00000260743 | ENSP00000305974 | Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. | Solute carrier organic anion transporter family member 1A2; Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin. | 0.601 |
CALHM2 | UGT3A1 | ENSP00000260743 | ENSP00000274278 | Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. | UDP-glucuronosyltransferase 3A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family. | 0.558 |
CALHM2 | UGT3A2 | ENSP00000260743 | ENSP00000282507 | Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. | UDP-glucuronosyltransferase 3A2; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family. | 0.558 |