TMEM260 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AURKAIP1	TMEM260	ENSP00000342676	ENSP00000261556	Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down- regulation through proteasome-dependent degradation.	Transmembrane protein 260; Belongs to the TMEM260 family.	0.489
CYP2C18	TMEM260	ENSP00000285979	ENSP00000261556	Cytochrome P450 2C18; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Transmembrane protein 260; Belongs to the TMEM260 family.	0.727
HEATR4	SH2D4A	ENSP00000450444	ENSP00000265807	HEAT repeat containing 4.	SH2 domain-containing protein 4A; Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T- cell development and function.	0.521
HEATR4	TMEM260	ENSP00000450444	ENSP00000261556	HEAT repeat containing 4.	Transmembrane protein 260; Belongs to the TMEM260 family.	0.565
MYH1	MYH3	ENSP00000226207	ENSP00000464317	Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin-3; Muscle contraction.	0.994
MYH1	MYH4	ENSP00000226207	ENSP00000255381	Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin-4; Muscle contraction.	0.995
MYH1	MYH7	ENSP00000226207	ENSP00000347507	Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle.	0.995
MYH1	TMEM260	ENSP00000226207	ENSP00000261556	Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Transmembrane protein 260; Belongs to the TMEM260 family.	0.764
MYH3	MYH1	ENSP00000464317	ENSP00000226207	Myosin-3; Muscle contraction.	Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.994
MYH3	MYH4	ENSP00000464317	ENSP00000255381	Myosin-3; Muscle contraction.	Myosin-4; Muscle contraction.	0.999
MYH3	MYH7	ENSP00000464317	ENSP00000347507	Myosin-3; Muscle contraction.	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle.	0.994
MYH3	TMEM260	ENSP00000464317	ENSP00000261556	Myosin-3; Muscle contraction.	Transmembrane protein 260; Belongs to the TMEM260 family.	0.884
MYH4	MYH1	ENSP00000255381	ENSP00000226207	Myosin-4; Muscle contraction.	Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.995
MYH4	MYH3	ENSP00000255381	ENSP00000464317	Myosin-4; Muscle contraction.	Myosin-3; Muscle contraction.	0.999
MYH4	MYH7	ENSP00000255381	ENSP00000347507	Myosin-4; Muscle contraction.	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle.	0.999
MYH4	TMEM260	ENSP00000255381	ENSP00000261556	Myosin-4; Muscle contraction.	Transmembrane protein 260; Belongs to the TMEM260 family.	0.850
MYH7	MYH1	ENSP00000347507	ENSP00000226207	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle.	Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.995
MYH7	MYH3	ENSP00000347507	ENSP00000464317	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle.	Myosin-3; Muscle contraction.	0.994
MYH7	MYH4	ENSP00000347507	ENSP00000255381	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle.	Myosin-4; Muscle contraction.	0.999
MYH7	MYLK2	ENSP00000347507	ENSP00000365162	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle.	Myosin light chain kinase 2, skeletal/cardiac muscle; Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N-terminus of a myosin light chain; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.	0.683