node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADGRL2 | CLVS1 | ENSP00000359765 | ENSP00000428402 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2). | 0.426 |
ADGRL2 | IGSF21 | ENSP00000359765 | ENSP00000251296 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | Immunoglobulin superfamily member 21; Involved in synaptic inhibition in the brain. Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2. | 0.406 |
ADGRL2 | LRMDA | ENSP00000359765 | ENSP00000480240 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation. | 0.695 |
ADGRL2 | PALMD | ENSP00000359765 | ENSP00000263174 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | Palmdelphin. | 0.442 |
ARSJ | KLHL31 | ENSP00000320219 | ENSP00000359942 | Arylsulfatase family member J. | Kelch-like protein 31; Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE). | 0.447 |
ARSJ | PALMD | ENSP00000320219 | ENSP00000263174 | Arylsulfatase family member J. | Palmdelphin. | 0.469 |
C12orf45 | PALMD | ENSP00000447057 | ENSP00000263174 | Uncharacterized protein C12orf45; Chromosome 12 open reading frame 45. | Palmdelphin. | 0.541 |
CLVS1 | ADGRL2 | ENSP00000428402 | ENSP00000359765 | Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2). | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | 0.426 |
CLVS1 | IGSF21 | ENSP00000428402 | ENSP00000251296 | Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2). | Immunoglobulin superfamily member 21; Involved in synaptic inhibition in the brain. Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2. | 0.530 |
CLVS1 | LRMDA | ENSP00000428402 | ENSP00000480240 | Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2). | Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation. | 0.476 |
CLVS1 | PALMD | ENSP00000428402 | ENSP00000263174 | Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2). | Palmdelphin. | 0.475 |
IGSF21 | ADGRL2 | ENSP00000251296 | ENSP00000359765 | Immunoglobulin superfamily member 21; Involved in synaptic inhibition in the brain. Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2. | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | 0.406 |
IGSF21 | CLVS1 | ENSP00000251296 | ENSP00000428402 | Immunoglobulin superfamily member 21; Involved in synaptic inhibition in the brain. Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2. | Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2). | 0.530 |
IGSF21 | LRMDA | ENSP00000251296 | ENSP00000480240 | Immunoglobulin superfamily member 21; Involved in synaptic inhibition in the brain. Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2. | Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation. | 0.478 |
IGSF21 | PALMD | ENSP00000251296 | ENSP00000263174 | Immunoglobulin superfamily member 21; Involved in synaptic inhibition in the brain. Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2. | Palmdelphin. | 0.459 |
KLHL31 | ARSJ | ENSP00000359942 | ENSP00000320219 | Kelch-like protein 31; Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE). | Arylsulfatase family member J. | 0.447 |
KLHL31 | PALMD | ENSP00000359942 | ENSP00000263174 | Kelch-like protein 31; Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE). | Palmdelphin. | 0.446 |
LRMDA | ADGRL2 | ENSP00000480240 | ENSP00000359765 | Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation. | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | 0.695 |
LRMDA | CLVS1 | ENSP00000480240 | ENSP00000428402 | Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation. | Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2). | 0.476 |
LRMDA | IGSF21 | ENSP00000480240 | ENSP00000251296 | Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation. | Immunoglobulin superfamily member 21; Involved in synaptic inhibition in the brain. Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2. | 0.478 |