STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTIF2Translation initiation factor IF-2, mitochondrial; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (727 aa)    
Predicted Functional Partners:
MRPS9
Mitochondrial ribosomal protein S9.
  
 0.993
MRPS16
Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
   
 0.992
MRPS6
Mitochondrial ribosomal protein S6.
   
 0.992
MRPS5
Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.
   
 0.991
MRPS10
Mitochondrial ribosomal protein S10; Belongs to the universal ribosomal protein uS10 family.
   
 0.990
MRPS11
Mitochondrial ribosomal protein S11.
   
 0.989
MRPL9
Mitochondrial ribosomal protein L9.
   
 0.989
MTIF3
Translation initiation factor IF-3, mitochondrial; IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins.
   
 0.987
MRPS12
Mitochondrial ribosomal protein S12.
  
 0.987
MRPL2
Mitochondrial ribosomal protein L2; Belongs to the universal ribosomal protein uL2 family.
   
 0.986
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.