node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C17orf97 | GATA3 | ENSP00000353245 | ENSP00000368632 | Protein LIAT1; May be involved in ATE1-mediated N-terminal arginylation. | Trans-acting T-cell-specific transcription factor GATA-3; Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. | 0.690 |
C17orf97 | KRT5 | ENSP00000353245 | ENSP00000252242 | Protein LIAT1; May be involved in ATE1-mediated N-terminal arginylation. | Keratin, type II cytoskeletal 5; Keratin 5; Belongs to the intermediate filament family. | 0.824 |
C17orf97 | KRT7 | ENSP00000353245 | ENSP00000329243 | Protein LIAT1; May be involved in ATE1-mediated N-terminal arginylation. | Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Belongs to the intermediate filament family. | 0.960 |
C17orf97 | UPK2 | ENSP00000353245 | ENSP00000264031 | Protein LIAT1; May be involved in ATE1-mediated N-terminal arginylation. | Uroplakin-2; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM (By similarity). | 0.585 |
C17orf97 | UPK3A | ENSP00000353245 | ENSP00000216211 | Protein LIAT1; May be involved in ATE1-mediated N-terminal arginylation. | Uroplakin-3a; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity). | 0.654 |
FOXR1 | UPK2 | ENSP00000314806 | ENSP00000264031 | Forkhead box R1. | Uroplakin-2; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM (By similarity). | 0.519 |
GATA3 | C17orf97 | ENSP00000368632 | ENSP00000353245 | Trans-acting T-cell-specific transcription factor GATA-3; Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. | Protein LIAT1; May be involved in ATE1-mediated N-terminal arginylation. | 0.690 |
GATA3 | KRT20 | ENSP00000368632 | ENSP00000167588 | Trans-acting T-cell-specific transcription factor GATA-3; Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. | Keratin, type I cytoskeletal 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity). | 0.725 |
GATA3 | KRT5 | ENSP00000368632 | ENSP00000252242 | Trans-acting T-cell-specific transcription factor GATA-3; Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. | Keratin, type II cytoskeletal 5; Keratin 5; Belongs to the intermediate filament family. | 0.675 |
GATA3 | KRT7 | ENSP00000368632 | ENSP00000329243 | Trans-acting T-cell-specific transcription factor GATA-3; Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. | Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Belongs to the intermediate filament family. | 0.743 |
GATA3 | UPK2 | ENSP00000368632 | ENSP00000264031 | Trans-acting T-cell-specific transcription factor GATA-3; Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. | Uroplakin-2; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM (By similarity). | 0.572 |
GATA3 | UPK3A | ENSP00000368632 | ENSP00000216211 | Trans-acting T-cell-specific transcription factor GATA-3; Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. | Uroplakin-3a; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity). | 0.447 |
KRT20 | GATA3 | ENSP00000167588 | ENSP00000368632 | Keratin, type I cytoskeletal 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity). | Trans-acting T-cell-specific transcription factor GATA-3; Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. | 0.725 |
KRT20 | UPK1A | ENSP00000167588 | ENSP00000478942 | Keratin, type I cytoskeletal 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity). | Uroplakin-1a; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity); Belongs to the tetraspanin (TM4SF) family. | 0.620 |
KRT20 | UPK1B | ENSP00000167588 | ENSP00000264234 | Keratin, type I cytoskeletal 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity). | Uroplakin-1b; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity); Belongs to the tetraspanin (TM4SF) family. | 0.537 |
KRT20 | UPK2 | ENSP00000167588 | ENSP00000264031 | Keratin, type I cytoskeletal 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity). | Uroplakin-2; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM (By similarity). | 0.705 |
KRT20 | UPK3A | ENSP00000167588 | ENSP00000216211 | Keratin, type I cytoskeletal 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity). | Uroplakin-3a; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity). | 0.728 |
KRT5 | C17orf97 | ENSP00000252242 | ENSP00000353245 | Keratin, type II cytoskeletal 5; Keratin 5; Belongs to the intermediate filament family. | Protein LIAT1; May be involved in ATE1-mediated N-terminal arginylation. | 0.824 |
KRT5 | GATA3 | ENSP00000252242 | ENSP00000368632 | Keratin, type II cytoskeletal 5; Keratin 5; Belongs to the intermediate filament family. | Trans-acting T-cell-specific transcription factor GATA-3; Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. | 0.675 |
KRT5 | KRT7 | ENSP00000252242 | ENSP00000329243 | Keratin, type II cytoskeletal 5; Keratin 5; Belongs to the intermediate filament family. | Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Belongs to the intermediate filament family. | 0.462 |