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STRINGSTRING
EFHD1 protein (human) - STRING interaction network
"EFHD1" - EF-hand domain-containing protein D1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFHD1EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation (By similarity); EF-hand domain containing (239 aa)    
Predicted Functional Partners:
RHAG
Ammonium transporter Rh type A; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. Involved in ammonia transport across the erythrocyte membrane. Seems to act in monovalent cation transport; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily (409 aa)
           
  0.766
ERMN
Ermin; Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity) (297 aa)
     
   
  0.698
AMN1
Protein AMN1 homolog; Antagonist of mitotic exit network 1 homolog (258 aa)
     
   
  0.544
STXBP5L
Syntaxin-binding protein 5-like; May play a role in vesicle trafficking and exocytosis; Belongs to the WD repeat L(2)GL family (1186 aa)
     
   
  0.536
KNDC1
Protein very KIND; RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pathway linking RAS and MAP2 (By similarity). May be involved in cellular senescence (1749 aa)
     
   
  0.522
ERGIC2
Endoplasmic reticulum-Golgi intermediate compartment protein 2; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the ERGIC family (377 aa)
           
  0.505
NKAIN1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1; Sodium/potassium transporting ATPase interacting 1 (207 aa)
     
   
  0.494
OPN5
Opsin-5; Opsin receptors (354 aa)
       
 
  0.492
FAM19A2
Protein FAM19A2; Family with sequence similarity 19 member A2, C-C motif chemokine like (131 aa)
           
  0.488
TLK2
Serine/threonine-protein kinase tousled-like 2; Serine/threonine-protein kinase involved in the process of chromatin assembly and probably also DNA replication, transcription, repair, and chromosome segregation. Phosphorylates the chromatin assembly factors ASF1A AND ASF1B. Phosphorylation of ASF1A prevents its proteasome-mediated degradation, thereby enhancing chromatin assembly. Negative regulator of amino acid starvation-induced autophagy (772 aa)
           
  0.485
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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