STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR108G protein-coupled receptor 108. (543 aa)    
Predicted Functional Partners:
SCAMP2
Secretory carrier-associated membrane protein 2; Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface; Belongs to the SCAMP family.
   
    0.766
KIAA0319L
Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R.
   
  
 0.659
CNPPD1
Protein CNPPD1; Cyclin Pas1/PHO80 domain containing 1.
   
    0.636
GPR152
Probable G-protein coupled receptor 152; Orphan receptor.
      
 0.631
GPR137
Integral membrane protein GPR137; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes. May play a role in autophagy ; Belongs to the GPR137 family.
   
  
 0.556
GPR137B
Integral membrane protein GPR137B; Lysosomal integral membrane protein that regulates the localization and activity of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Interacts with Rag GTPases and increases the lysosomial localization and activity of Rag GTPases and thereby regulates mTORC1 translocation and activity in lysosome. Involved in the regulation of lysosomal morphology and autophagy.
   
  
 0.555
TPRA1
Transmembrane protein adipocyte associated 1; Belongs to the UPF0359 family.
   
  
 0.543
GPR137C
Integral membrane protein GPR137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes; Belongs to the GPR137 family.
      
 0.529
GPR171
Probable G-protein coupled receptor 171; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.494
TM9SF2
Transmembrane 9 superfamily member 2; In the intracellular compartments, may function as a channel or small molecule transporter.
   
  
 0.458
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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