KIAA1109 protein (human) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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co-expression

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Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAD1	KIAA1109	ENSP00000296513	ENSP00000264501	Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity).	Transmembrane protein KIAA1109; KIAA1109.	0.964
ADAD1	LPP	ENSP00000296513	ENSP00000491657	Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity).	Lipoma-preferred partner; May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.	0.643
ADAD1	SH2B3	ENSP00000296513	ENSP00000345492	Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity).	SH2B adapter protein 3; Links T-cell receptor activation signal to phospholipase C- gamma-1, GRB2 and phosphatidylinositol 3-kinase.	0.623
ADAD1	TAGAP	ENSP00000296513	ENSP00000356033	Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity).	T-cell activation Rho GTPase-activating protein; May function as a GTPase-activating protein and may play important roles during T-cell activation.	0.663
C1orf43	KIAA1109	ENSP00000357507	ENSP00000264501	Uncharacterized protein C1orf43; Chromosome 1 open reading frame 43.	Transmembrane protein KIAA1109; KIAA1109.	0.888
CCDC28A	KIAA1109	ENSP00000479060	ENSP00000264501	Coiled-coil domain containing 28A.	Transmembrane protein KIAA1109; KIAA1109.	0.880
ENO1	KIAA1109	ENSP00000495530	ENSP00000264501	Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. Belongs to the enolase family.	Transmembrane protein KIAA1109; KIAA1109.	0.657
KIAA1109	ADAD1	ENSP00000264501	ENSP00000296513	Transmembrane protein KIAA1109; KIAA1109.	Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity).	0.964
KIAA1109	C1orf43	ENSP00000264501	ENSP00000357507	Transmembrane protein KIAA1109; KIAA1109.	Uncharacterized protein C1orf43; Chromosome 1 open reading frame 43.	0.888
KIAA1109	CCDC28A	ENSP00000264501	ENSP00000479060	Transmembrane protein KIAA1109; KIAA1109.	Coiled-coil domain containing 28A.	0.880
KIAA1109	ENO1	ENSP00000264501	ENSP00000495530	Transmembrane protein KIAA1109; KIAA1109.	Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. Belongs to the enolase family.	0.657
KIAA1109	LPP	ENSP00000264501	ENSP00000491657	Transmembrane protein KIAA1109; KIAA1109.	Lipoma-preferred partner; May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.	0.665
KIAA1109	MRGBP	ENSP00000264501	ENSP00000359518	Transmembrane protein KIAA1109; KIAA1109.	MRG/MORF4L-binding protein; Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...]	0.681
KIAA1109	PIGG	ENSP00000264501	ENSP00000415203	Transmembrane protein KIAA1109; KIAA1109.	GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.	0.720
KIAA1109	SH2B3	ENSP00000264501	ENSP00000345492	Transmembrane protein KIAA1109; KIAA1109.	SH2B adapter protein 3; Links T-cell receptor activation signal to phospholipase C- gamma-1, GRB2 and phosphatidylinositol 3-kinase.	0.670
KIAA1109	TAGAP	ENSP00000264501	ENSP00000356033	Transmembrane protein KIAA1109; KIAA1109.	T-cell activation Rho GTPase-activating protein; May function as a GTPase-activating protein and may play important roles during T-cell activation.	0.723
KIAA1109	WDR12	ENSP00000264501	ENSP00000261015	Transmembrane protein KIAA1109; KIAA1109.	Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.666
LPP	ADAD1	ENSP00000491657	ENSP00000296513	Lipoma-preferred partner; May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.	Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity).	0.643
LPP	KIAA1109	ENSP00000491657	ENSP00000264501	Lipoma-preferred partner; May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.	Transmembrane protein KIAA1109; KIAA1109.	0.665
LPP	SH2B3	ENSP00000491657	ENSP00000345492	Lipoma-preferred partner; May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.	SH2B adapter protein 3; Links T-cell receptor activation signal to phospholipase C- gamma-1, GRB2 and phosphatidylinositol 3-kinase.	0.577