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ARSB protein (human) - STRING interaction network
"ARSB" - Arylsulfatase B in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
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Textmining
[Homology]
Score
ARSBArylsulfatase B; Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation. Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium. In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity); Belongs to the sulfatase family (533 aa)    
Predicted Functional Partners:
SUMF1
Sulfatase-modifying factor 1; Using molecular oxygen and an unidentified reducing agent, oxidizes a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also called C(alpha)-formylglycine. Known substrates include GALNS, ARSA, STS and ARSE; Belongs to the sulfatase-modifying factor family (374 aa)
 
   
  0.976
IDUA
Alpha-L-iduronidase; Iduronidase, alpha-L- (653 aa)
         
  0.966
GUSB
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family (651 aa)
       
  0.962
SUMF2
Sulfatase-modifying factor 2; Lacks formyl-glycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activation of sulfatases by SUMF1 (358 aa)
 
   
  0.951
ARSK
Arylsulfatase family member K; Sulfatases (536 aa)
   
 
  0.949
ARSH
Arylsulfatase family member H; Sulfatases (562 aa)
   
 
0.941
ARSD
Arylsulfatase D; Sulfatases (593 aa)
   
 
0.937
GNS
N-acetylglucosamine-6-sulfatase; Glucosamine-6-sulfatase; Belongs to the sulfatase family (552 aa)
   
 
0.937
ARSA
Arylsulfatase A; Hydrolyzes cerebroside sulfate; Belongs to the sulfatase family (509 aa)
   
   
0.936
STS
Steryl-sulfatase; Conversion of sulfated steroid precursors to estrogens during pregnancy; Sulfatases (583 aa)
   
   
0.934
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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