node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHMP7 | R3HCC1 | ENSP00000380794 | ENSP00000265806 | Charged multivesicular body protein 7; ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase. Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Plays a role in the endosomal sorting pathway. | R3H domain and coiled-coil containing 1. | 0.678 |
DMAP1 | R3HCC1 | ENSP00000361363 | ENSP00000265806 | DNA methyltransferase 1-associated protein 1; Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucle [...] | R3H domain and coiled-coil containing 1. | 0.468 |
FAM149A | MOCS1 | ENSP00000227065 | ENSP00000344794 | Protein FAM149A; Family with sequence similarity 149 member A. | Cyclic pyranopterin monophosphate synthase; Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). MOCS1A catalyzes the cyclization of GTP to (8S)- 3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and MOCS1B catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'- triphosphate to cPMP; In the C-terminal section; belongs to the MoaC family. | 0.442 |
FAM149A | R3HCC1 | ENSP00000227065 | ENSP00000265806 | Protein FAM149A; Family with sequence similarity 149 member A. | R3H domain and coiled-coil containing 1. | 0.440 |
GPKOW | R3HCC1 | ENSP00000156109 | ENSP00000265806 | G-patch domain and KOW motifs-containing protein; RNA-binding protein involved in pre-mRNA splicing. | R3H domain and coiled-coil containing 1. | 0.441 |
GPKOW | SNAP47 | ENSP00000156109 | ENSP00000314157 | G-patch domain and KOW motifs-containing protein; RNA-binding protein involved in pre-mRNA splicing. | Synaptosomal-associated protein 47; Plays a role in intracellular membrane fusion. | 0.438 |
MOCS1 | FAM149A | ENSP00000344794 | ENSP00000227065 | Cyclic pyranopterin monophosphate synthase; Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). MOCS1A catalyzes the cyclization of GTP to (8S)- 3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and MOCS1B catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'- triphosphate to cPMP; In the C-terminal section; belongs to the MoaC family. | Protein FAM149A; Family with sequence similarity 149 member A. | 0.442 |
MOCS1 | R3HCC1 | ENSP00000344794 | ENSP00000265806 | Cyclic pyranopterin monophosphate synthase; Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). MOCS1A catalyzes the cyclization of GTP to (8S)- 3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and MOCS1B catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'- triphosphate to cPMP; In the C-terminal section; belongs to the MoaC family. | R3H domain and coiled-coil containing 1. | 0.434 |
R3HCC1 | CHMP7 | ENSP00000265806 | ENSP00000380794 | R3H domain and coiled-coil containing 1. | Charged multivesicular body protein 7; ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase. Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Plays a role in the endosomal sorting pathway. | 0.678 |
R3HCC1 | DMAP1 | ENSP00000265806 | ENSP00000361363 | R3H domain and coiled-coil containing 1. | DNA methyltransferase 1-associated protein 1; Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucle [...] | 0.468 |
R3HCC1 | FAM149A | ENSP00000265806 | ENSP00000227065 | R3H domain and coiled-coil containing 1. | Protein FAM149A; Family with sequence similarity 149 member A. | 0.440 |
R3HCC1 | GPKOW | ENSP00000265806 | ENSP00000156109 | R3H domain and coiled-coil containing 1. | G-patch domain and KOW motifs-containing protein; RNA-binding protein involved in pre-mRNA splicing. | 0.441 |
R3HCC1 | MOCS1 | ENSP00000265806 | ENSP00000344794 | R3H domain and coiled-coil containing 1. | Cyclic pyranopterin monophosphate synthase; Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). MOCS1A catalyzes the cyclization of GTP to (8S)- 3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and MOCS1B catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'- triphosphate to cPMP; In the C-terminal section; belongs to the MoaC family. | 0.434 |
R3HCC1 | SNAP47 | ENSP00000265806 | ENSP00000314157 | R3H domain and coiled-coil containing 1. | Synaptosomal-associated protein 47; Plays a role in intracellular membrane fusion. | 0.459 |
R3HCC1 | SVOPL | ENSP00000265806 | ENSP00000405482 | R3H domain and coiled-coil containing 1. | Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily. | 0.509 |
R3HCC1 | TMEM63C | ENSP00000265806 | ENSP00000298351 | R3H domain and coiled-coil containing 1. | Calcium permeable stress-gated cation channel 1; Acts as an osmosensitive calcium-permeable cation channel. Required for the functional integrity of the kidney glomerular filtration barrier (By similarity). Belongs to the CSC1 (TC 1.A.17) family. | 0.428 |
R3HCC1 | YIPF3 | ENSP00000265806 | ENSP00000361499 | R3H domain and coiled-coil containing 1. | Protein YIPF3, 36 kDa form III; Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis. | 0.432 |
R3HCC1 | ZNF414 | ENSP00000265806 | ENSP00000377504 | R3H domain and coiled-coil containing 1. | Zinc finger protein 414; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.420 |
SNAP47 | GPKOW | ENSP00000314157 | ENSP00000156109 | Synaptosomal-associated protein 47; Plays a role in intracellular membrane fusion. | G-patch domain and KOW motifs-containing protein; RNA-binding protein involved in pre-mRNA splicing. | 0.438 |
SNAP47 | R3HCC1 | ENSP00000314157 | ENSP00000265806 | Synaptosomal-associated protein 47; Plays a role in intracellular membrane fusion. | R3H domain and coiled-coil containing 1. | 0.459 |