node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANAPC2 | TTLL1 | ENSP00000314004 | ENSP00000266254 | Anaphase-promoting complex subunit 2; Together with the RING-H2 protein ANAPC11, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The CDC20-APC/C complex positively re [...] | Probable tubulin polyglutamylase TTLL1; Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin (By similarity). | 0.682 |
C11orf49 | KIAA1841 | ENSP00000367878 | ENSP00000385579 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Uncharacterized protein KIAA1841; KIAA1841. | 0.627 |
C11orf49 | LRRC49 | ENSP00000367878 | ENSP00000453273 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | 0.906 |
C11orf49 | NICN1 | ENSP00000367878 | ENSP00000273598 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Nicolin-1; Nicolin 1. | 0.818 |
C11orf49 | TBC1D19 | ENSP00000367878 | ENSP00000264866 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | TBC1 domain family member 19; May act as a GTPase-activating protein for Rab family protein(s). | 0.647 |
C11orf49 | TPGS1 | ENSP00000367878 | ENSP00000352265 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity). | 0.753 |
C11orf49 | TPGS2 | ENSP00000367878 | ENSP00000464780 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Tubulin polyglutamylase complex subunit 2. | 0.854 |
C11orf49 | TTLL1 | ENSP00000367878 | ENSP00000266254 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Probable tubulin polyglutamylase TTLL1; Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin (By similarity). | 0.872 |
CEP41 | TTLL1 | ENSP00000223208 | ENSP00000266254 | Centrosomal protein of 41 kDa; Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium. Belongs to the CEP41 family. | Probable tubulin polyglutamylase TTLL1; Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin (By similarity). | 0.644 |
EDC3 | TTLL1 | ENSP00000497737 | ENSP00000266254 | Enhancer of mRNA-decapping protein 3; Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping. May play a role in spermiogenesis and oogenesis. | Probable tubulin polyglutamylase TTLL1; Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin (By similarity). | 0.861 |
KIAA1841 | C11orf49 | ENSP00000385579 | ENSP00000367878 | Uncharacterized protein KIAA1841; KIAA1841. | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | 0.627 |
KIAA1841 | LRRC49 | ENSP00000385579 | ENSP00000453273 | Uncharacterized protein KIAA1841; KIAA1841. | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | 0.805 |
KIAA1841 | NICN1 | ENSP00000385579 | ENSP00000273598 | Uncharacterized protein KIAA1841; KIAA1841. | Nicolin-1; Nicolin 1. | 0.828 |
KIAA1841 | TPGS1 | ENSP00000385579 | ENSP00000352265 | Uncharacterized protein KIAA1841; KIAA1841. | Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity). | 0.610 |
KIAA1841 | TTLL1 | ENSP00000385579 | ENSP00000266254 | Uncharacterized protein KIAA1841; KIAA1841. | Probable tubulin polyglutamylase TTLL1; Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin (By similarity). | 0.789 |
LRRC49 | C11orf49 | ENSP00000453273 | ENSP00000367878 | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | 0.906 |
LRRC49 | KIAA1841 | ENSP00000453273 | ENSP00000385579 | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | Uncharacterized protein KIAA1841; KIAA1841. | 0.805 |
LRRC49 | NICN1 | ENSP00000453273 | ENSP00000273598 | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | Nicolin-1; Nicolin 1. | 0.981 |
LRRC49 | TBC1D19 | ENSP00000453273 | ENSP00000264866 | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | TBC1 domain family member 19; May act as a GTPase-activating protein for Rab family protein(s). | 0.803 |
LRRC49 | TPGS1 | ENSP00000453273 | ENSP00000352265 | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity). | 0.987 |