ARMH4 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARMH1	ARMH2	ENSP00000420716	ENSP00000454913	Armadillo like helical domain containing 1.	Armadillo-like helical domain-containing protein 2; Armadillo like helical domain containing 2.	0.554
ARMH1	ARMH4	ENSP00000420716	ENSP00000267485	Armadillo like helical domain containing 1.	Armadillo-like helical domain-containing protein 4; Armadillo like helical domain containing 4.	0.692
ARMH2	ARMH1	ENSP00000454913	ENSP00000420716	Armadillo-like helical domain-containing protein 2; Armadillo like helical domain containing 2.	Armadillo like helical domain containing 1.	0.554
ARMH2	ARMH4	ENSP00000454913	ENSP00000267485	Armadillo-like helical domain-containing protein 2; Armadillo like helical domain containing 2.	Armadillo-like helical domain-containing protein 4; Armadillo like helical domain containing 4.	0.607
ARMH4	ARMH1	ENSP00000267485	ENSP00000420716	Armadillo-like helical domain-containing protein 4; Armadillo like helical domain containing 4.	Armadillo like helical domain containing 1.	0.692
ARMH4	ARMH2	ENSP00000267485	ENSP00000454913	Armadillo-like helical domain-containing protein 4; Armadillo like helical domain containing 4.	Armadillo-like helical domain-containing protein 2; Armadillo like helical domain containing 2.	0.607
ARMH4	BMPR1A	ENSP00000267485	ENSP00000361107	Armadillo-like helical domain-containing protein 4; Armadillo like helical domain containing 4.	Bone morphogenetic protein receptor type-1A; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.404
ARMH4	FGFR1	ENSP00000267485	ENSP00000393312	Armadillo-like helical domain-containing protein 4; Armadillo like helical domain containing 4.	Fibroblast growth factor receptor 1; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 lea [...]	0.401
ARMH4	TCEAL4	ENSP00000267485	ENSP00000361712	Armadillo-like helical domain-containing protein 4; Armadillo like helical domain containing 4.	Transcription elongation factor A protein-like 4; May be involved in transcriptional regulation.	0.403
ARMH4	TSACC	ENSP00000267485	ENSP00000357238	Armadillo-like helical domain-containing protein 4; Armadillo like helical domain containing 4.	TSSK6-activating co-chaperone protein; Co-chaperone that facilitates HSP-mediated activation of TSSK6; Belongs to the TSACC family.	0.537
ARMH4	VIRMA	ENSP00000267485	ENSP00000297591	Armadillo-like helical domain-containing protein 4; Armadillo like helical domain containing 4.	Protein virilizer homolog; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3'-UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites. Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3'-UTR near the stop codon corr [...]	0.460
ARMH4	XKR4	ENSP00000267485	ENSP00000328326	Armadillo-like helical domain-containing protein 4; Armadillo like helical domain containing 4.	XK-related protein 4; XK related 4.	0.426
BMPR1A	ARMH4	ENSP00000361107	ENSP00000267485	Bone morphogenetic protein receptor type-1A; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Armadillo-like helical domain-containing protein 4; Armadillo like helical domain containing 4.	0.404
FGFR1	ARMH4	ENSP00000393312	ENSP00000267485	Fibroblast growth factor receptor 1; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 lea [...]	Armadillo-like helical domain-containing protein 4; Armadillo like helical domain containing 4.	0.401
FGFR1	VIRMA	ENSP00000393312	ENSP00000297591	Fibroblast growth factor receptor 1; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 lea [...]	Protein virilizer homolog; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3'-UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites. Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3'-UTR near the stop codon corr [...]	0.457
TCEAL4	ARMH4	ENSP00000361712	ENSP00000267485	Transcription elongation factor A protein-like 4; May be involved in transcriptional regulation.	Armadillo-like helical domain-containing protein 4; Armadillo like helical domain containing 4.	0.403
TCEAL4	TSACC	ENSP00000361712	ENSP00000357238	Transcription elongation factor A protein-like 4; May be involved in transcriptional regulation.	TSSK6-activating co-chaperone protein; Co-chaperone that facilitates HSP-mediated activation of TSSK6; Belongs to the TSACC family.	0.441
TSACC	ARMH4	ENSP00000357238	ENSP00000267485	TSSK6-activating co-chaperone protein; Co-chaperone that facilitates HSP-mediated activation of TSSK6; Belongs to the TSACC family.	Armadillo-like helical domain-containing protein 4; Armadillo like helical domain containing 4.	0.537
TSACC	TCEAL4	ENSP00000357238	ENSP00000361712	TSSK6-activating co-chaperone protein; Co-chaperone that facilitates HSP-mediated activation of TSSK6; Belongs to the TSACC family.	Transcription elongation factor A protein-like 4; May be involved in transcriptional regulation.	0.441
VIRMA	ARMH4	ENSP00000297591	ENSP00000267485	Protein virilizer homolog; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3'-UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites. Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3'-UTR near the stop codon corr [...]	Armadillo-like helical domain-containing protein 4; Armadillo like helical domain containing 4.	0.460