FAM181A protein (human) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Knowledge-based Evidence

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Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFAP47	FAM181A	ENSP00000367922	ENSP00000267594	Cilia and flagella associated protein 47.	Protein FAM181A; Family with sequence similarity 181 member A.	0.535
CFAP47	IQCK	ENSP00000367922	ENSP00000324901	Cilia and flagella associated protein 47.	IQ motif containing K.	0.470
CFAP47	LRRC43	ENSP00000367922	ENSP00000344233	Cilia and flagella associated protein 47.	Leucine-rich repeat-containing protein 43; Leucine rich repeat containing 43.	0.841
FAM181A	CFAP47	ENSP00000267594	ENSP00000367922	Protein FAM181A; Family with sequence similarity 181 member A.	Cilia and flagella associated protein 47.	0.535
FAM181A	IQCK	ENSP00000267594	ENSP00000324901	Protein FAM181A; Family with sequence similarity 181 member A.	IQ motif containing K.	0.474
FAM181A	LRRC43	ENSP00000267594	ENSP00000344233	Protein FAM181A; Family with sequence similarity 181 member A.	Leucine-rich repeat-containing protein 43; Leucine rich repeat containing 43.	0.603
FAM181A	MRI1	ENSP00000267594	ENSP00000040663	Protein FAM181A; Family with sequence similarity 181 member A.	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.	0.483
FAM181A	OR6X1	ENSP00000267594	ENSP00000333724	Protein FAM181A; Family with sequence similarity 181 member A.	Olfactory receptor 6X1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	0.469
FAM181A	PRIMA1	ENSP00000267594	ENSP00000376848	Protein FAM181A; Family with sequence similarity 181 member A.	Proline-rich membrane anchor 1; Required to anchor acetylcholinesterase (ACHE) to the basal lamina of the neuromuscular junction and to the membrane of neuronal synapses in brain. Also able to organize ACHE into tetramers (By similarity).	0.498
FAM181A	SIPA1L1	ENSP00000267594	ENSP00000450832	Protein FAM181A; Family with sequence similarity 181 member A.	Signal-induced proliferation-associated 1-like protein 1; Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits DLG4 to F-actin. Contributes to the regulation of dendritic spine morphogenesis (By similarity).	0.470
FAM181A	TEAD4	ENSP00000267594	ENSP00000352926	Protein FAM181A; Family with sequence similarity 181 member A.	Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell [...]	0.920
FAM181A	TEX43	ENSP00000267594	ENSP00000349669	Protein FAM181A; Family with sequence similarity 181 member A.	Testis-expressed protein 43; Testis expressed 43.	0.556
FAM181A	TTC7B	ENSP00000267594	ENSP00000336127	Protein FAM181A; Family with sequence similarity 181 member A.	Tetratricopeptide repeat protein 7B; Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis. In the complex, plays a central role in bridging PI4KA to EFR3B and FAM126A, via direct interactions.	0.497
IQCK	CFAP47	ENSP00000324901	ENSP00000367922	IQ motif containing K.	Cilia and flagella associated protein 47.	0.470
IQCK	FAM181A	ENSP00000324901	ENSP00000267594	IQ motif containing K.	Protein FAM181A; Family with sequence similarity 181 member A.	0.474
IQCK	LRRC43	ENSP00000324901	ENSP00000344233	IQ motif containing K.	Leucine-rich repeat-containing protein 43; Leucine rich repeat containing 43.	0.513
IQCK	TEX43	ENSP00000324901	ENSP00000349669	IQ motif containing K.	Testis-expressed protein 43; Testis expressed 43.	0.407
LRRC43	CFAP47	ENSP00000344233	ENSP00000367922	Leucine-rich repeat-containing protein 43; Leucine rich repeat containing 43.	Cilia and flagella associated protein 47.	0.841
LRRC43	FAM181A	ENSP00000344233	ENSP00000267594	Leucine-rich repeat-containing protein 43; Leucine rich repeat containing 43.	Protein FAM181A; Family with sequence similarity 181 member A.	0.603
LRRC43	IQCK	ENSP00000344233	ENSP00000324901	Leucine-rich repeat-containing protein 43; Leucine rich repeat containing 43.	IQ motif containing K.	0.513