STRINGSTRING
WDR93 protein (human) - STRING interaction network
"WDR93" - WD repeat-containing protein 93 in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
WDR93WD repeat-containing protein 93; WD repeat domain containing (686 aa)    
Predicted Functional Partners:
MESP2
Mesoderm posterior protein 2; Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together w [...] (397 aa)
           
  0.715
CLHC1
Clathrin heavy chain linker domain containing 1 (586 aa)
     
   
  0.675
FAM120AOS
Uncharacterized protein FAM120AOS; Family with sequence similarity 120A opposite strand (256 aa)
           
  0.645
HDDC3
Guanosine-3’,5’-bis(diphosphate) 3’-pyrophosphohydrolase MESH1; ppGpp hydrolyzing enzyme involved in starvation response (179 aa)
           
  0.626
ARPIN
Arpin; Regulates actin polymerization by inhibiting the actin- nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors. Participates in an incoherent feedforward loop at the lamellipodium tip where it inhibits the ARP2/2 complex in response to Rac signaling and where Rac also stimulates actin polymerization through the WAVE complex. Involved in steering cell migration by controlling its directional persistence; Belongs to the Arpin family (226 aa)
           
  0.621
CFAP221
Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis; Cilia and flagella associated (840 aa)
     
   
  0.612
C12orf4
Protein C12orf4; Plays a role in mast cell degranulation (552 aa)
           
  0.588
C12orf55
Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella (3096 aa)
           
  0.576
LIPA
Lysosomal acid lipase/cholesteryl ester hydrolase; Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor- mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation; Belongs to the AB hydrolase superfamily. Lipase family (399 aa)
           
  0.561
DAB2IP
Disabled homolog 2-interacting protein; Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF), interferon [...] (1132 aa)
           
  0.557
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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