SECTM1 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD300LG	ROBO4	ENSP00000321005	ENSP00000304945	CMRF35-like molecule 9; Receptor which may mediate L-selectin-dependent lymphocyte rollings. Binds SELL in a calcium dependent manner. Binds lymphocyte (By similarity).	Roundabout homolog 4; Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity). Involved in the maintenance of endothelial barrier organization and function.	0.527
CD300LG	SECTM1	ENSP00000321005	ENSP00000269389	CMRF35-like molecule 9; Receptor which may mediate L-selectin-dependent lymphocyte rollings. Binds SELL in a calcium dependent manner. Binds lymphocyte (By similarity).	Secreted and transmembrane protein 1; May be involved in thymocyte signaling.	0.533
CD7	SECTM1	ENSP00000312027	ENSP00000269389	T-cell antigen CD7; Not yet known.	Secreted and transmembrane protein 1; May be involved in thymocyte signaling.	0.993
ROBO4	CD300LG	ENSP00000304945	ENSP00000321005	Roundabout homolog 4; Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity). Involved in the maintenance of endothelial barrier organization and function.	CMRF35-like molecule 9; Receptor which may mediate L-selectin-dependent lymphocyte rollings. Binds SELL in a calcium dependent manner. Binds lymphocyte (By similarity).	0.527
ROBO4	SECTM1	ENSP00000304945	ENSP00000269389	Roundabout homolog 4; Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity). Involved in the maintenance of endothelial barrier organization and function.	Secreted and transmembrane protein 1; May be involved in thymocyte signaling.	0.443
ROBO4	VMO1	ENSP00000304945	ENSP00000328397	Roundabout homolog 4; Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity). Involved in the maintenance of endothelial barrier organization and function.	Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family.	0.548
SECTM1	CD300LG	ENSP00000269389	ENSP00000321005	Secreted and transmembrane protein 1; May be involved in thymocyte signaling.	CMRF35-like molecule 9; Receptor which may mediate L-selectin-dependent lymphocyte rollings. Binds SELL in a calcium dependent manner. Binds lymphocyte (By similarity).	0.533
SECTM1	CD7	ENSP00000269389	ENSP00000312027	Secreted and transmembrane protein 1; May be involved in thymocyte signaling.	T-cell antigen CD7; Not yet known.	0.993
SECTM1	ROBO4	ENSP00000269389	ENSP00000304945	Secreted and transmembrane protein 1; May be involved in thymocyte signaling.	Roundabout homolog 4; Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity). Involved in the maintenance of endothelial barrier organization and function.	0.443
SECTM1	TEX19	ENSP00000269389	ENSP00000331500	Secreted and transmembrane protein 1; May be involved in thymocyte signaling.	Testis-expressed protein 19; Required during spermatogenesis and placenta development, participating in the repression of retrotransposable elements and prevent their mobilization. Collaborates with the Piwi-interacting RNA (piRNA) pathway, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins. Interacts with Piwi proteins and directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer- independent mechanism and are primarily derived from transposons and other repeated sequence elemen [...]	0.504
SECTM1	VMO1	ENSP00000269389	ENSP00000328397	Secreted and transmembrane protein 1; May be involved in thymocyte signaling.	Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family.	0.520
TEX19	SECTM1	ENSP00000331500	ENSP00000269389	Testis-expressed protein 19; Required during spermatogenesis and placenta development, participating in the repression of retrotransposable elements and prevent their mobilization. Collaborates with the Piwi-interacting RNA (piRNA) pathway, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins. Interacts with Piwi proteins and directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer- independent mechanism and are primarily derived from transposons and other repeated sequence elemen [...]	Secreted and transmembrane protein 1; May be involved in thymocyte signaling.	0.504
VMO1	ROBO4	ENSP00000328397	ENSP00000304945	Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family.	Roundabout homolog 4; Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity). Involved in the maintenance of endothelial barrier organization and function.	0.548
VMO1	SECTM1	ENSP00000328397	ENSP00000269389	Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family.	Secreted and transmembrane protein 1; May be involved in thymocyte signaling.	0.520