node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IGSF5 | ILDR2 | ENSP00000369962 | ENSP00000271417 | Immunoglobulin superfamily member 5; Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity); Belongs to the immunoglobulin superfamily. | Immunoglobulin-like domain-containing receptor 2; May be involved in lipid homeostasis and ER stress pathways. Belongs to the immunoglobulin superfamily. LISCH7 family. | 0.455 |
IGSF5 | MARVELD2 | ENSP00000369962 | ENSP00000323264 | Immunoglobulin superfamily member 5; Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity); Belongs to the immunoglobulin superfamily. | MARVEL domain-containing protein 2; Plays a role in the formation of tricellular tight junctions and of epithelial barriers (By similarity). Required for normal hearing via its role in the separation of the endolymphatic and perilymphatic spaces of the organ of Corti in the inner ear, and for normal survival of hair cells in the organ of Corti. | 0.653 |
IGSF5 | OCLN | ENSP00000369962 | ENSP00000347379 | Immunoglobulin superfamily member 5; Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity); Belongs to the immunoglobulin superfamily. | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions. | 0.906 |
ILDR2 | IGSF5 | ENSP00000271417 | ENSP00000369962 | Immunoglobulin-like domain-containing receptor 2; May be involved in lipid homeostasis and ER stress pathways. Belongs to the immunoglobulin superfamily. LISCH7 family. | Immunoglobulin superfamily member 5; Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity); Belongs to the immunoglobulin superfamily. | 0.455 |
ILDR2 | LRIT3 | ENSP00000271417 | ENSP00000469759 | Immunoglobulin-like domain-containing receptor 2; May be involved in lipid homeostasis and ER stress pathways. Belongs to the immunoglobulin superfamily. LISCH7 family. | Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3; Plays a role in the synapse formation and synaptic transmission between cone photoreceptor cells and retinal bipolar cells (By similarity). Required for normal transmission of a light-evoked stimulus from the cone photoreceptor cells to the ON-bipolar cells and ON-ganglion cells in the inner retina. Required in retinal ON-bipolar cells for normal localization of the cation channel TRPM1 at dendrite tips (By similarity). Seems to play a specific role in synaptic contacts made by ON-bipolar cel [...] | 0.459 |
ILDR2 | LSR | ENSP00000271417 | ENSP00000480821 | Immunoglobulin-like domain-containing receptor 2; May be involved in lipid homeostasis and ER stress pathways. Belongs to the immunoglobulin superfamily. LISCH7 family. | Lipolysis-stimulated lipoprotein receptor; Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity); Belongs to the immunoglobulin superfamily. LISCH7 family. | 0.463 |
ILDR2 | MARVELD2 | ENSP00000271417 | ENSP00000323264 | Immunoglobulin-like domain-containing receptor 2; May be involved in lipid homeostasis and ER stress pathways. Belongs to the immunoglobulin superfamily. LISCH7 family. | MARVEL domain-containing protein 2; Plays a role in the formation of tricellular tight junctions and of epithelial barriers (By similarity). Required for normal hearing via its role in the separation of the endolymphatic and perilymphatic spaces of the organ of Corti in the inner ear, and for normal survival of hair cells in the organ of Corti. | 0.894 |
ILDR2 | OCLN | ENSP00000271417 | ENSP00000347379 | Immunoglobulin-like domain-containing receptor 2; May be involved in lipid homeostasis and ER stress pathways. Belongs to the immunoglobulin superfamily. LISCH7 family. | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions. | 0.660 |
ILDR2 | POGK | ENSP00000271417 | ENSP00000356849 | Immunoglobulin-like domain-containing receptor 2; May be involved in lipid homeostasis and ER stress pathways. Belongs to the immunoglobulin superfamily. LISCH7 family. | Pogo transposable element derived with KRAB domain. | 0.511 |
ILDR2 | TRA2A | ENSP00000271417 | ENSP00000297071 | Immunoglobulin-like domain-containing receptor 2; May be involved in lipid homeostasis and ER stress pathways. Belongs to the immunoglobulin superfamily. LISCH7 family. | Transformer-2 protein homolog alpha; Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. | 0.581 |
ILDR2 | TRA2B | ENSP00000271417 | ENSP00000416959 | Immunoglobulin-like domain-containing receptor 2; May be involved in lipid homeostasis and ER stress pathways. Belongs to the immunoglobulin superfamily. LISCH7 family. | Transformer-2 protein homolog beta; Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA. Belongs to the splicing factor SR family. | 0.498 |
ILDR2 | ZFP69 | ENSP00000271417 | ENSP00000361791 | Immunoglobulin-like domain-containing receptor 2; May be involved in lipid homeostasis and ER stress pathways. Belongs to the immunoglobulin superfamily. LISCH7 family. | Zinc finger protein 69 homolog; Putative transcription factor that appears to regulate lipid metabolism; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.506 |
ILDR2 | ZNF70 | ENSP00000271417 | ENSP00000339314 | Immunoglobulin-like domain-containing receptor 2; May be involved in lipid homeostasis and ER stress pathways. Belongs to the immunoglobulin superfamily. LISCH7 family. | Zinc finger protein 70; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.450 |
LRIT3 | ILDR2 | ENSP00000469759 | ENSP00000271417 | Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3; Plays a role in the synapse formation and synaptic transmission between cone photoreceptor cells and retinal bipolar cells (By similarity). Required for normal transmission of a light-evoked stimulus from the cone photoreceptor cells to the ON-bipolar cells and ON-ganglion cells in the inner retina. Required in retinal ON-bipolar cells for normal localization of the cation channel TRPM1 at dendrite tips (By similarity). Seems to play a specific role in synaptic contacts made by ON-bipolar cel [...] | Immunoglobulin-like domain-containing receptor 2; May be involved in lipid homeostasis and ER stress pathways. Belongs to the immunoglobulin superfamily. LISCH7 family. | 0.459 |
LSR | ILDR2 | ENSP00000480821 | ENSP00000271417 | Lipolysis-stimulated lipoprotein receptor; Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity); Belongs to the immunoglobulin superfamily. LISCH7 family. | Immunoglobulin-like domain-containing receptor 2; May be involved in lipid homeostasis and ER stress pathways. Belongs to the immunoglobulin superfamily. LISCH7 family. | 0.463 |
LSR | MARVELD2 | ENSP00000480821 | ENSP00000323264 | Lipolysis-stimulated lipoprotein receptor; Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity); Belongs to the immunoglobulin superfamily. LISCH7 family. | MARVEL domain-containing protein 2; Plays a role in the formation of tricellular tight junctions and of epithelial barriers (By similarity). Required for normal hearing via its role in the separation of the endolymphatic and perilymphatic spaces of the organ of Corti in the inner ear, and for normal survival of hair cells in the organ of Corti. | 0.949 |
LSR | OCLN | ENSP00000480821 | ENSP00000347379 | Lipolysis-stimulated lipoprotein receptor; Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity); Belongs to the immunoglobulin superfamily. LISCH7 family. | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions. | 0.567 |
MARVELD2 | IGSF5 | ENSP00000323264 | ENSP00000369962 | MARVEL domain-containing protein 2; Plays a role in the formation of tricellular tight junctions and of epithelial barriers (By similarity). Required for normal hearing via its role in the separation of the endolymphatic and perilymphatic spaces of the organ of Corti in the inner ear, and for normal survival of hair cells in the organ of Corti. | Immunoglobulin superfamily member 5; Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity); Belongs to the immunoglobulin superfamily. | 0.653 |
MARVELD2 | ILDR2 | ENSP00000323264 | ENSP00000271417 | MARVEL domain-containing protein 2; Plays a role in the formation of tricellular tight junctions and of epithelial barriers (By similarity). Required for normal hearing via its role in the separation of the endolymphatic and perilymphatic spaces of the organ of Corti in the inner ear, and for normal survival of hair cells in the organ of Corti. | Immunoglobulin-like domain-containing receptor 2; May be involved in lipid homeostasis and ER stress pathways. Belongs to the immunoglobulin superfamily. LISCH7 family. | 0.894 |
MARVELD2 | LSR | ENSP00000323264 | ENSP00000480821 | MARVEL domain-containing protein 2; Plays a role in the formation of tricellular tight junctions and of epithelial barriers (By similarity). Required for normal hearing via its role in the separation of the endolymphatic and perilymphatic spaces of the organ of Corti in the inner ear, and for normal survival of hair cells in the organ of Corti. | Lipolysis-stimulated lipoprotein receptor; Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity); Belongs to the immunoglobulin superfamily. LISCH7 family. | 0.949 |