node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B3GNT5 | SLC10A6 | ENSP00000316173 | ENSP00000273905 | Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase; Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during emb [...] | Solute carrier family 10 member 6; Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | 0.489 |
B3GNT5 | TM4SF1 | ENSP00000316173 | ENSP00000304277 | Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase; Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during emb [...] | Transmembrane 4 L six family member 1; Belongs to the L6 tetraspanin family. | 0.439 |
EMP1 | SLC10A6 | ENSP00000256951 | ENSP00000273905 | Epithelial membrane protein 1. | Solute carrier family 10 member 6; Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | 0.425 |
EMP1 | TM4SF1 | ENSP00000256951 | ENSP00000304277 | Epithelial membrane protein 1. | Transmembrane 4 L six family member 1; Belongs to the L6 tetraspanin family. | 0.456 |
SLC10A6 | B3GNT5 | ENSP00000273905 | ENSP00000316173 | Solute carrier family 10 member 6; Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase; Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during emb [...] | 0.489 |
SLC10A6 | EMP1 | ENSP00000273905 | ENSP00000256951 | Solute carrier family 10 member 6; Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | Epithelial membrane protein 1. | 0.425 |
SLC10A6 | SLC10A7 | ENSP00000273905 | ENSP00000421275 | Solute carrier family 10 member 6; Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | Sodium/bile acid cotransporter 7; Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins, to produce a proper functioning extracellular matrix. Required for extracellular matrix mineralization. Also involved in the regulation of cellular calcium homeostasis. Does not show transport activity towards bile acids or steroid sulfates (including taurocholate, cholate, chenodeoxycholate, estrone-3-sulfate, dehydroepiandrosterone sulfate (DHEAS) and pregnenolone sulfate). Belongs to the bile acid:sodium symp [...] | 0.738 |
SLC10A6 | SLC22A11 | ENSP00000273905 | ENSP00000301891 | Solute carrier family 10 member 6; Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | Solute carrier family 22 member 11; Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds. | 0.481 |
SLC10A6 | SLC22A9 | ENSP00000273905 | ENSP00000279178 | Solute carrier family 10 member 6; Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | Solute carrier family 22 member 9; Sodium-independent organic anion transporter which exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones. It is also specifically activated by 3 to 5 carbons- containing short-chain fatty acids/SCFAs, including propionate, butyrate and valerate. May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs at the sinusoidal membrane of hepatocytes; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. | 0.505 |
SLC10A6 | SLCO2B1 | ENSP00000273905 | ENSP00000289575 | Solute carrier family 10 member 6; Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | Solute carrier organic anion transporter family member 2B1; Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost. | 0.426 |
SLC10A6 | STS | ENSP00000273905 | ENSP00000217961 | Solute carrier family 10 member 6; Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | Steryl-sulfatase; Catalyzes the conversion of sulfated steroid precursors, such as dehydroepiandrosterone sulfate (DHEA-S) and estrone sulfate to the free steroid. | 0.457 |
SLC10A6 | TM4SF1 | ENSP00000273905 | ENSP00000304277 | Solute carrier family 10 member 6; Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | Transmembrane 4 L six family member 1; Belongs to the L6 tetraspanin family. | 0.441 |
SLC10A7 | SLC10A6 | ENSP00000421275 | ENSP00000273905 | Sodium/bile acid cotransporter 7; Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins, to produce a proper functioning extracellular matrix. Required for extracellular matrix mineralization. Also involved in the regulation of cellular calcium homeostasis. Does not show transport activity towards bile acids or steroid sulfates (including taurocholate, cholate, chenodeoxycholate, estrone-3-sulfate, dehydroepiandrosterone sulfate (DHEAS) and pregnenolone sulfate). Belongs to the bile acid:sodium symp [...] | Solute carrier family 10 member 6; Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | 0.738 |
SLC22A11 | SLC10A6 | ENSP00000301891 | ENSP00000273905 | Solute carrier family 22 member 11; Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds. | Solute carrier family 10 member 6; Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | 0.481 |
SLC22A11 | SLCO2B1 | ENSP00000301891 | ENSP00000289575 | Solute carrier family 22 member 11; Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds. | Solute carrier organic anion transporter family member 2B1; Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost. | 0.677 |
SLC22A9 | SLC10A6 | ENSP00000279178 | ENSP00000273905 | Solute carrier family 22 member 9; Sodium-independent organic anion transporter which exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones. It is also specifically activated by 3 to 5 carbons- containing short-chain fatty acids/SCFAs, including propionate, butyrate and valerate. May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs at the sinusoidal membrane of hepatocytes; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. | Solute carrier family 10 member 6; Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | 0.505 |
SLC22A9 | SLCO2B1 | ENSP00000279178 | ENSP00000289575 | Solute carrier family 22 member 9; Sodium-independent organic anion transporter which exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones. It is also specifically activated by 3 to 5 carbons- containing short-chain fatty acids/SCFAs, including propionate, butyrate and valerate. May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs at the sinusoidal membrane of hepatocytes; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. | Solute carrier organic anion transporter family member 2B1; Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost. | 0.711 |
SLCO2B1 | SLC10A6 | ENSP00000289575 | ENSP00000273905 | Solute carrier organic anion transporter family member 2B1; Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost. | Solute carrier family 10 member 6; Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | 0.426 |
SLCO2B1 | SLC22A11 | ENSP00000289575 | ENSP00000301891 | Solute carrier organic anion transporter family member 2B1; Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost. | Solute carrier family 22 member 11; Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds. | 0.677 |
SLCO2B1 | SLC22A9 | ENSP00000289575 | ENSP00000279178 | Solute carrier organic anion transporter family member 2B1; Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost. | Solute carrier family 22 member 9; Sodium-independent organic anion transporter which exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones. It is also specifically activated by 3 to 5 carbons- containing short-chain fatty acids/SCFAs, including propionate, butyrate and valerate. May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs at the sinusoidal membrane of hepatocytes; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. | 0.711 |