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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPATA9Spermatogenesis-associated protein 9; May play a role in testicular development/spermatogenesis and may be an important factor in male infertility. (254 aa)    
Predicted Functional Partners:
CCDC38
Coiled-coil domain containing 38.
   
  
 0.626
LRMDA
Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation.
      
 0.581
ARMC2
Armadillo repeat-containing protein 2; Required for sperm flagellum axoneme organization and function (By similarity). Involved in axonemal central pair complex assembly and/or stability (By similarity).
   
  
 0.572
C16orf95
Uncharacterized protein C16orf95; Chromosome 16 open reading frame 95.
      
 0.544
CFDP1
Craniofacial development protein 1; May play a role during embryogenesis.
      
 0.541
SPATC1
Speriolin; Spermatogenesis and centriole associated 1; Belongs to the speriolin family.
   
  
 0.514
GSTCD
Glutathione S-transferase C-terminal domain containing; Belongs to the GSTCD family.
      
 0.507
SPATA46
Spermatogenesis-associated protein 46; Plays a role in spermiogenesis and fertilization.
      
 0.497
CBY2
Chibby family member 2.
   
  
 0.496
ASB6
Ankyrin repeat and SOCS box protein 6; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
      
 0.494
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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